Family main features
PLEKHA1 (Pleckstrin Homology Domain Containing A1) is a protein involved in intracellular signaling and cytoskeletal organization. The pleckstrin homology (PH) domain is a common protein domain involved in targeting proteins to cell membranes by binding to phosphoinositides. PLEKHA1 has been implicated in various cellular processes, including cell migration, survival, and signaling. It is expressed in many tissues, but its expression levels and functions can vary significantly depending on the cell type and physiological conditions. Research has shown that PLEKHA1 plays a role in disease mechanisms, particularly in cancer and diabetes, making it a potential therapeutic target.
PLEKHA1 is characterized by the presence of a pleckstrin homology (PH) domain, which is essential for its function:
PLEKHA1 is part of the Pleckstrin Homology Domain Containing (PLEKHA) family. This family consists of several proteins that share the PH domain and are involved in various signaling and cytoskeletal functions. Other members of the PLEKHA family include PLEKHA2, PLEKHA3, and PLEKHA4, each with distinct but sometimes overlapping functions.
PLEKHA1 is involved in several key cellular processes:
Dysregulation or mutations in PLEKHA1 have been linked to several diseases:
PLEKHA1 (Pleckstrin Homology Domain Containing A1) is a protein that plays a crucial role in intracellular signaling, cytoskeletal organization, and membrane dynamics. It is characterized by its PH domain, which binds to phosphoinositides, targeting the protein to specific cell membranes. PLEKHA1 is involved in critical cellular processes such as signal transduction, cell migration, adhesion, and vesicle trafficking. Dysregulation of PLEKHA1 has been linked to various diseases, including cancer, diabetes, and potentially neurological disorders, highlighting its importance in cellular function and its potential as a therapeutic target. Understanding the mechanisms of PLEKHA1 function and regulation provides valuable insights into its role in health and disease.
Pleckstrin homology domain containing A1 (PLEKHA1)
PLEKHA1, TAPP1, PH domain-containing family A member 1,Tandem PH domain-containing protein 1
Pleckstrin homology domain containing A2 (PLEKHA2)
TAPP2,PH domain-containing family A member 2,Tandem PH domain-containing protein 2
Pleckstrin homology domain containing A3 (PLEKHA3)
FAPP1,PH domain-containing family A member 3,Phosphatidylinositol-four-phosphate adapter protein 1
Pleckstrin homology domain containing A4 (PLEKHA4)
PEPP1,PH domain-containing family A member 4,Phosphoinositol 3-phosphate-binding protein 1
Pleckstrin homology domain containing A5 (PLEKHA5)
PLEKHA5, KIAA1686, PEPP2,PH domain-containing family A member 5,Phosphoinositol 3-phosphate-binding protein 2
Pleckstrin homology domain containing A6 (PLEKHA6)
KIAA0969, PEPP3,PH domain-containing family A member 6,Phosphoinositol 3-phosphate-binding protein 3,PEPP-3
Pleckstrin homology domain containing A7 (PLEKHA7)
PH domain-containing family A member 7
Pleckstrin homology domain containing A8 (PLEKHA8)
FAPP2,PH domain-containing family A member 8,Phosphatidylinositol-four-phosphate adapter protein 2,FAPP-2
Pleckstrin homology domain-containing A8 pseudogene 1 (PLEKHA8P1)
PLEKHA8P1,PLEKHA9,FAPP2,FAPP-2,Hfapp2,PLEKHA8,Putative protein PLEKHA9
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits) relacionados con PLEKHA - Pleckstrin homology domain containing A1
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Esta página contiene 55 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | PLEKHA1 | abx382284 | Human Pleckstrin Homology Domain Containing A1 (PLEKHA1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q9HB21 | RUO |
Abbexa | PLEKHA2 | abx539029 | Human Pleckstrin homology domain-containing family A member 2 (PLEKHA2) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q9HB19 | RUO | ||
Abbexa | PLEKHA3 | abx382285 | Human Pleckstrin Homology Domain Containing A3 (PLEKHA3) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.313 ng/ml - 20 ng/ml | < 0.188 ng/ml | 687.5 | 96 tests | Q9HB20 | RUO |
Abbexa | PLEKHA4 | abx539033 | Human Pleckstrin homology domain-containing family A member 4 (PLEKHA4) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q9H4M7 | RUO | ||
Abbexa | PLEKHA5 | abx382286 | Human Pleckstrin Homology Domain Containing A5 (PLEKHA5) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q9HAU0 | RUO |
Abbexa | PLEKHA6 | abx539037 | Human Pleckstrin homology domain-containing family A member 6 (PLEKHA6) ELISA Kit | Human | Serum,Plasma,Tissue homogenates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q9Y2H5 | RUO | ||
Abbexa | PLEKHA7 | abx539039 | Human Pleckstrin homology domain-containing family A member 7 (PLEKHA7) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q6IQ23 | RUO | ||
Abbexa | PLEKHA8 | abx382287 | Human Pleckstrin Homology Domain Containing A8 (PLEKHA8) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.313 ng/ml - 20 ng/ml | < 0.188 ng/ml | 687.5 | 96 tests | Q96JA3 | RUO |
Abbexa | PLEKHA8P1 | abx382288 | Human Pleckstrin Homology Domain Containing A8 Pseudogene 1 (PLEKHA9) ELISA Kit | Human | Serum,Plasma,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | O95397 | RUO |
Abbexa | PLEKHA1 | abx539027 | Mouse Pleckstrin homology domain-containing family A member 1 (PLEKHA1) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8BUL6 | RUO | ||
Abbexa | PLEKHA2 | abx539030 | Mouse Pleckstrin homology domain-containing family A member 2 (PLEKHA2) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q9ERS5 | RUO | ||
Abbexa | PLEKHA3 | abx539032 | Mouse Pleckstrin homology domain-containing family A member 3 (PLEKHA3) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q9ERS4 | RUO | ||
Abbexa | PLEKHA4 | abx539034 | Mouse Pleckstrin homology domain-containing family A member 4 (PLEKHA4) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8VC98 | RUO | ||
Abbexa | PLEKHA6 | abx539038 | Mouse Pleckstrin homology domain-containing family A member 6 (PLEKHA6) ELISA Kit | Mouse | Serum,Plasma,Tissue homogenates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q7TQG1 | RUO | ||
Abbexa | PLEKHA7 | abx539040 | Mouse Pleckstrin homology domain-containing family A member 7 (PLEKHA7) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q3UIL6 | RUO | ||
Abbexa | PLEKHA8 | abx539044 | Mouse Pleckstrin homology domain-containing family A member 8 (PLEKHA8) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q80W71 | RUO | ||
Abbexa | PLEKHA4 | abx539035 | Rat Pleckstrin Homology Domain-Containing Family A Member 4 (PLEKHA4) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P60669 | RUO | ||
Abbexa | PLEKHA8 | abx539045 | Rat Pleckstrin Homology Domain Containing A8 (PLEKHA8) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | D3ZY60 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | PLEKHA5 | abx430809 | Pleckstrin Homology Domain Containing A5 (PLEKHA5) Antibody | Polyclonal | Goat | Pleckstrin Homology Domain Containing A5 (PLEKHA5) | Unconjugated | P-ELISA | 250 | 200 µl | RUO | |||
FineTest | PLEKHA1 | FNab06534 | anti- PLEKHA1 antibody | human | polyclonal | Rabbit | pleckstrin homology domain containing, family A(phosphoinositide binding specific) member 1 | IgG | Unconjugated | ELISA, WB, IHC | 100µg | Q9HB21 | RUO | |
FineTest | PLEKHA3 | FNab06535 | anti- PLEKHA3 antibody | human | polyclonal | Rabbit | pleckstrin homology domain containing, family A(phosphoinositide binding specific) member 3 | IgG | Unconjugated | ELISA, WB | 100µg | Q9HB20 | RUO | |
FineTest | PLEKHA5 | FNab06536 | anti- PLEKHA5 antibody | human | polyclonal | Rabbit | pleckstrin homology domain containing, family A member 5 | IgG | Unconjugated | ELISA, WB | 100µg | Q9HAU0 | RUO | |
FineTest | PLEKHA8 | FNab06537 | anti- PLEKHA8 antibody | human | polyclonal | Rabbit | pleckstrin homology domain containing, family A(phosphoinositide binding specific) member 8 | IgG | Unconjugated | ELISA, WB, IHC | 100µg | Q96JA3 | RUO | |
FineTest | PLEKHA8P1 | FNab06538 | anti- PLEKHA9 antibody | human | polyclonal | Rabbit | pleckstrin homology domain containing, family A(phosphoinositide binding specific) member 9 | IgG | Unconjugated | ELISA, WB | 100µg | O95397 | RUO | |
Abbexa | PLEKHA1 | abx030118 | Pleckstrin Homology Domain Containing A1 (PLEKHA1) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A1 (PLEKHA1) | Unconjugated | ELISA, WB | 250 | 80 µl | Q9HB21 | RUO | |
Abbexa | PLEKHA1 | abx104679 | Pleckstrin Homology Domain Containing Family A, Member 1 (PLEKHA1) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing Family A, Member 1 (PLEKHA1) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | RUO | ||
Abbexa | PLEKHA1 | abx321051 | Pleckstrin Homology Domain Containing A1 (PLEKHA1) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A1 (PLEKHA1) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q9HB21 | RUO | |
Abbexa | PLEKHA1 | abx321937 | Pleckstrin Homology Domain Containing A1 (PLEKHA1) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A1 (PLEKHA1) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | Q9HB21 | RUO | |
Abbexa | PLEKHA1 | abx402486 | Pleckstrin homology domain-containing family A member 1 (PLEKHA1) Antibody | Human | Monoclonal | Rabbit | Pleckstrin homology domain-containing family A member 1 (PLEKHA1) | Unconjugated | ELISA, WB | 287.5 | 50 µl | Q9HB21 | RUO | |
Abbexa | PLEKHA1 | abx114542 | Pleckstrin Homology Domain Containing A1 (PLEKHA1) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A1 (PLEKHA1) | Unconjugated | ELISA, WB, IHC | 612.5 | 100 µl | Q9HB21 | RUO | |
Abbexa | PLEKHA1 | abx236534 | Pleckstrin Homology Domain Containing A1 (PLEKHA1) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A1 (PLEKHA1) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | Q9HB21 | RUO | |
Abbexa | PLEKHA3 | abx236535 | Pleckstrin Homology Domain Containing A3 (PLEKHA3) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A3 (PLEKHA3) | Unconjugated | ELISA, WB | 350 | 100 µg | Q9HB20 | RUO | |
Abbexa | PLEKHA3 | abx114543 | Pleckstrin Homology Domain Containing A3 (PLEKHA3) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A3 (PLEKHA3) | Unconjugated | ELISA, WB | 612.5 | 100 µl | Q9HB20 | RUO | |
Abbexa | PLEKHA4 | abx026435 | Pleckstrin Homology Domain-Containing Family A Member 4 (PLEKHA4) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain-Containing Family A Member 4 (PLEKHA4) | Unconjugated | ELISA, WB, IHC, FCM | 250 | 80 µl | Q9H4M7 | RUO | |
Abbexa | PLEKHA5 | abx114546 | Pleckstrin Homology Domain Containing A5 (PLEKHA5) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A5 (PLEKHA5) | Unconjugated | ELISA, WB | 612.5 | 100 µl | Q9HAU0 | RUO | |
Abbexa | PLEKHA5 | abx236536 | Pleckstrin Homology Domain Containing A5 (PLEKHA5) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A5 (PLEKHA5) | Unconjugated | ELISA, WB | 350 | 100 µg | Q9HAU0 | RUO | |
Abbexa | PLEKHA6 | abx029805 | Pleckstrin Homology Domain-Containing Family A Member 6 (PLEKHA6) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain-Containing Family A Member 6 (PLEKHA6) | Unconjugated | ELISA, WB | 250 | 80 µl | Q9Y2H5 | RUO | |
Abbexa | PLEKHA7 | abx314539 | PLEKHA7 Antibody (HRP) | Human | Polyclonal | Rabbit | PLEKHA7 | HRP | ELISA | 162.5 | 20 µg | Q6IQ23 | RUO | |
Abbexa | PLEKHA7 | abx300996 | Pleckstrin Homology Domain-Containing Family A Member 7 (PLEKHA7) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain-Containing Family A Member 7 (PLEKHA7) | Unconjugated | ELISA, IF/ICC | 162.5 | 20 µg | Q6IQ23 | RUO | |
Abbexa | PLEKHA7 | abx314541 | PLEKHA7 Antibody (Biotin) | Human | Polyclonal | Rabbit | PLEKHA7 | Biotin | ELISA | 162.5 | 20 µg | Q6IQ23 | RUO | |
Abbexa | PLEKHA7 | abx314540 | PLEKHA7 Antibody (FITC) | Human | Polyclonal | Rabbit | PLEKHA7 | FITC | 162.5 | 20 µg | Q6IQ23 | RUO | ||
Abbexa | PLEKHA8 | abx310472 | Pleckstrin Homology Domain Containing A8 (PLEKHA8) Antibody (HRP) | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A8 (PLEKHA8) | HRP | ELISA | 162.5 | 20 µg | Q96JA3 | RUO | |
Abbexa | PLEKHA8 | abx310473 | Pleckstrin Homology Domain Containing A8 (PLEKHA8) Antibody (FITC) | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A8 (PLEKHA8) | FITC | 162.5 | 20 µg | Q96JA3 | RUO | ||
Abbexa | PLEKHA8 | abx036146 | Pleckstrin Homology Domain Containing A8 (PLEKHA8) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A8 (PLEKHA8) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | PLEKHA8 | abx310474 | Pleckstrin Homology Domain Containing A8 (PLEKHA8) Antibody (Biotin) | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A8 (PLEKHA8) | Biotin | ELISA | 162.5 | 20 µg | Q96JA3 | RUO | |
Abbexa | PLEKHA8 | abx030189 | Pleckstrin Homology Domain Containing A8 (PLEKHA8) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A8 (PLEKHA8) | Unconjugated | ELISA, WB | 281.25 | 80 µl | Q96JA3 | RUO | |
Abbexa | PLEKHA8 | abx318411 | Pleckstrin Homology Domain Containing A8 (PLEKHA8) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A8 (PLEKHA8) | Unconjugated | ELISA, WB, IHC | 162.5 | 20 µg | Q96JA3 | RUO | |
Abbexa | PLEKHA8 | abx236537 | Pleckstrin Homology Domain Containing A8 (PLEKHA8) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A8 (PLEKHA8) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | Q96JA3 | RUO | |
Abbexa | PLEKHA8 | abx114544 | Pleckstrin Homology Domain Containing A8 (Plekha8) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A8 (Plekha8) | Unconjugated | ELISA, WB, IHC | 612.5 | 100 µl | Q96JA3 | RUO | |
Abbexa | PLEKHA8P1 | abx036997 | Pleckstrin Homology Domain Containing A8 Pseudogene 1 (PLEKHA9) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A8 Pseudogene 1 (PLEKHA9) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | PLEKHA8P1 | abx236538 | Pleckstrin Homology Domain Containing A8 Pseudogene 1 (PLEKHA9) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A8 Pseudogene 1 (PLEKHA9) | Unconjugated | ELISA, WB | 350 | 100 µg | O95397 | RUO | |
Abbexa | PLEKHA8P1 | abx114545 | Pleckstrin Homology Domain Containing A8 Pseudogene 1 (PLEKHA9) Antibody | Human | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing A8 Pseudogene 1 (PLEKHA9) | Unconjugated | ELISA, WB | 612.5 | 100 µl | O95397 | RUO | |
Abbexa | PLEKHA1 | abx129422 | Pleckstrin Homology Domain Containing Family A, Member 1 (PLEKHA1) Antibody | Mouse | Polyclonal | Rabbit | Pleckstrin Homology Domain Containing Family A, Member 1 (PLEKHA1) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | PLEKHA1 | abx068604 | Human Pleckstrin Homology Domain Containing Family A, Member 1 (PLEKHA1) Protein | Human | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | Q9HB21 | RUO | |
Abbexa | PLEKHA1 | abx168385 | Mouse Pleckstrin Homology Domain Containing Family A, Member 1 (PLEKHA1) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | RUO |
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