Mouse Pleckstrin homology domain-containing family A member 6 (PLEKHA6) ELISA Kit

Este producto es parte de PLEKHA - Pleckstrin homology domain containing A1
Mouse Pleckstrin homology domain-containing family A member 6 (PLEKHA6) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for PLEKHA6

proveedor

Abbexa

reference

abx539038

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Pleckstrin homology domain-containing family A member 6 (PLEKHA6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Pleckstrin homology domain-containing family A member 6 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.


Background

PLEKHA6 is a member of the pleckstrin homology (PH) domain-containing protein family that interacts with phosphoinositides, enabling its recruitment to plasma and endosomal membranes for the regulation of intracellular signaling and vesicle trafficking. It functions as a scaffold protein that coordinates the localization and activity of signaling molecules involved in cytoskeletal dynamics, endocytosis, and cellular adhesion. PLEKHA6 is expressed in epithelial, endothelial, and immune cells, where it regulates processes like cell migration, polarity, and tissue remodeling. Dysregulation of PLEKHA6 has been implicated in cancer metastasis and inflammatory disorders due to its role in actin reorganization and cell adhesion dynamics. Knockout studies demonstrate defects in membrane trafficking, impaired cellular adhesion, and reduced migration, highlighting its essential role in coordinating phosphoinositide-mediated signaling pathways, cytoskeletal organization, and cellular polarity.

Características del producto

category

ELISA Kits


immunogen target

Pleckstrin homology domain-containing family A member 6 (PLEKHA6)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.


size 1

96 tests


alias

KIAA0969, PEPP3,PH domain-containing family A member 6,Phosphoinositol 3-phosphate-binding protein 3,PEPP-3


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

PLEKHA6


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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