Mouse Pleckstrin homology domain-containing family A member 6 (PLEKHA6) ELISA Kit

Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for PLEKHA6
proveedor
Abbexareference
abx539038Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Pleckstrin homology domain-containing family A member 6 (PLEKHA6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Pleckstrin homology domain-containing family A member 6 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Background
PLEKHA6 is a member of the pleckstrin homology (PH) domain-containing protein family that interacts with phosphoinositides, enabling its recruitment to plasma and endosomal membranes for the regulation of intracellular signaling and vesicle trafficking. It functions as a scaffold protein that coordinates the localization and activity of signaling molecules involved in cytoskeletal dynamics, endocytosis, and cellular adhesion. PLEKHA6 is expressed in epithelial, endothelial, and immune cells, where it regulates processes like cell migration, polarity, and tissue remodeling. Dysregulation of PLEKHA6 has been implicated in cancer metastasis and inflammatory disorders due to its role in actin reorganization and cell adhesion dynamics. Knockout studies demonstrate defects in membrane trafficking, impaired cellular adhesion, and reduced migration, highlighting its essential role in coordinating phosphoinositide-mediated signaling pathways, cytoskeletal organization, and cellular polarity.
Características del producto
category
ELISA Kits
immunogen target
Pleckstrin homology domain-containing family A member 6 (PLEKHA6)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
size 1
96 tests
alias
KIAA0969, PEPP3,PH domain-containing family A member 6,Phosphoinositol 3-phosphate-binding protein 3,PEPP-3
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
PLEKHA6
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
Pleckstrin Homology Domain-Containing Family A Member 6 (PLEKHA6) Antibody

proveedor
Abbexareference
abx029805Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalPEPP3 contains an N-terminal pleckstrin homology (PH) domain. It shares significant homology with PEPP1 and PEPP2 only i...
292.5€ (80 µl)
Ver másHuman Pleckstrin homology domain-containing family A member 6 (PLEKHA6) ELISA Kit

proveedor
Abbexareference
abx539037Tested Applications
ELISAreactivity
Humanstatus
RUOHuman Pleckstrin homology domain-containing family A member 6 (PLEKHA6) ELISA Kit is an ELISA Kit for the in vitro quant...
715€ (96 tests)
Ver másMouse Pleckstrin homology domain-containing family A member 6 (PLEKHA6) ELISA Kit

proveedor
Abbexareference
abx539038Tested Applications
ELISAreactivity
Mousestatus
RUOMouse Pleckstrin homology domain-containing family A member 6 (PLEKHA6) ELISA Kit is an ELISA Kit for the in vitro quant...
715€ (96 tests)
Ver más