Pleckstrin Homology Domain Containing A8 Pseudogene 1 (PLEKHA9) Antibody
357.5€ (100 µg)
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name
Pleckstrin Homology Domain Containing A8 Pseudogene 1 (PLEKHA9) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx036997
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the PLEKHA9 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Pleckstrin Homology Domain Containing A8 Pseudogene 1 (PLEKHA9) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | PLEKHA8P1,PLEKHA9,FAPP2,FAPP-2,Hfapp2,PLEKHA8,Putative protein PLEKHA9 |
| Background | Antibody anti-PLEKHA8P1 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
Pleckstrin homology domain-containing A8 pseudogene 1 (PLEKHA8P1) is a pseudogene derived from the parent gene PLEKHA8, which encodes a protein involved in membrane trafficking and phosphoinositide binding, particularly associated with intracellular vesicle dynamics and signaling pathways. Although PLEKHA8P1 lacks the ability to code for a functional protein, it may still play a regulatory role through mechanisms such as transcriptional interference, RNA-mediated regulation, or serving as a competing endogenous RNA to modulate the availability of microRNAs targeting its parental gene or related pathways. Pseudogenes like PLEKHA8P1 are increasingly recognized for their potential contributions to gene expression regulation and genome evolution, often serving as reservoirs of genetic diversity or influencing neighboring gene activity. PLEKHA8P1 has been implicated in studies exploring its expression patterns in specific tissues or disease states, with some evidence suggesting its dysregulation may correlate with pathological conditions, including cancer, where it might influence cellular signaling indirectly. Further investigation is required to elucidate its precise functional roles and potential contributions to the regulatory networks involving PLEKHA8 and other pleckstrin homology domain-containing proteins.
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