Mouse Pleckstrin homology domain-containing family A member 2 (PLEKHA2) ELISA Kit
715€ (96 tests)
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935106861
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name
Mouse Pleckstrin homology domain-containing family A member 2 (PLEKHA2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx539030
tested applications
ELISA
Description
Mouse Pleckstrin homology domain-containing family A member 2 (PLEKHA2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Pleckstrin homology domain-containing family A member 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Pleckstrin homology domain-containing family A member 2 (PLEKHA2) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9ERS5 |
| Gene ID | 83436 |
| Alias | TAPP2,PH domain-containing family A member 2,Tandem PH domain-containing protein 2 |
| Background | Elisa kits for PLEKHA2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PLEKHA2 is a lipid-binding protein that contains a pleckstrin homology (PH) domain with high specificity for phosphoinositides such as PI(3,4)P2, enabling it to localize to plasma membranes and mediate signaling events. It plays a key role in actin cytoskeletal dynamics, cellular migration, and immune cell signaling by recruiting cytoskeletal regulators and signaling molecules to membrane sites. PLEKHA2 is expressed in immune and endothelial cells, where it regulates processes such as phagocytosis, chemotaxis, and membrane ruffling during immune responses. It also participates in signaling pathways like PI3K/Akt, contributing to cell survival and proliferation. Dysregulation of PLEKHA2 has been associated with inflammatory diseases and cancer metastasis due to altered actin remodeling and immune cell dysfunction. Knockout studies demonstrate impaired actin polymerization, reduced immune cell migration, and defects in membrane organization, highlighting its role as a mediator of phosphoinositide-driven cellular responses.
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Human Pleckstrin homology domain-containing family A member 2 (PLEKHA2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Pleckstrin homology domain-containing family A member 2 (PLEKHA2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver ProductoMouse Pleckstrin homology domain-containing family A member 2 (PLEKHA2) ELISA Kit
Mouse Pleckstrin homology domain-containing family A member 2 (PLEKHA2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Pleckstrin homology domain-containing family A member 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver Producto