Mouse Pleckstrin homology domain-containing family A member 3 (PLEKHA3) ELISA Kit

Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for PLEKHA3
proveedor
Abbexareference
abx539032Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Pleckstrin homology domain-containing family A member 3 (PLEKHA3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Pleckstrin homology domain-containing family A member 3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
PLEKHA3 is a member of the pleckstrin homology (PH) domain-containing protein family that binds phosphoinositides, including PI(3,4)P2 and PI(4,5)P2, to regulate membrane targeting and intracellular signaling pathways. It is involved in processes such as cell polarity, membrane trafficking, and cytoskeletal organization, where it recruits signaling complexes to membrane compartments. PLEKHA3 is expressed in various tissues, including immune and epithelial cells, where it regulates endocytic vesicle transport, signal transduction, and cellular adhesion. It has been implicated in processes like epithelial-mesenchymal transition (EMT) and cancer progression, where its dysregulation promotes cell migration, invasion, and altered signaling dynamics. Knockdown studies reveal defects in endocytosis, impaired membrane recruitment of signaling proteins, and disrupted cytoskeletal organization, underscoring its critical role in phosphoinositide-mediated cellular signaling, vesicular trafficking, and cell polarity.
Características del producto
category
ELISA Kits
immunogen target
Pleckstrin homology domain-containing family A member 3 (PLEKHA3)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
FAPP1,PH domain-containing family A member 3,Phosphatidylinositol-four-phosphate adapter protein 1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
PLEKHA3
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
anti- PLEKHA3 antibody

proveedor
FineTestreference
FNab06535Tested Applications
ELISA, WBreactivity
human,mouse,ratstatus
RUOclonality
polyclonalInvolved in Golgi to cell surface membrane traffic. Induces membrane tubulation. Binds preferentially to phosphatidylino...
Precio a consultar
Ver másPleckstrin Homology Domain Containing A3 (PLEKHA3) Antibody

proveedor
Abbexareference
abx114543Tested Applications
ELISA, WBreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalPleckstrin Homology Domain Containing, Family A (Phosphoinositide Binding Specific) Member 3 Antibody is a Rabbit Polycl...
637€ (100 µl)
Ver másPleckstrin Homology Domain Containing A3 (PLEKHA3) Antibody

proveedor
Abbexareference
abx236535Tested Applications
ELISA, WBreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalPLEKHA3 Antibody is a Rabbit Polyclonal against PLEKHA3.
364€ (100 µg)
Ver más