Family main features
Interferon-Induced GTP-Binding Protein MX (MX) is a family of dynamin-like GTPases that are induced by type I interferons (IFNs) such as IFN-α and IFN-β, in response to viral infections. The induction of MX expression is mediated by the JAK-STAT signaling pathway, which leads to the activation of interferon-stimulated response elements (ISREs) in the promoter regions of MX genes. MX proteins are expressed in a wide range of cell types, including immune cells (e.g., macrophages, dendritic cells), epithelial cells, and fibroblasts. They typically contain a GTP-binding domain, a bundle signaling element, and a stalk region involved in oligomerization and interaction with cellular membranes. MX proteins form oligomeric complexes, such as dimers or higher-order oligomers, which are essential for their function in mediating antiviral activities. MX proteins play a crucial role in the host defense against viral infections by inhibiting viral replication and spread. They exert their antiviral effects through various mechanisms, including: Viral Nucleocapsid Disruption:,Viral Particle Budding Inhibition,Inhibition of Viral Transcription and Translation. MX proteins also play a role in modulating immune responses to viral infections. They can regulate the production of pro-inflammatory cytokines and chemokines, as well as the activation of immune cells such as macrophages and dendritic cells. Beyond their antiviral functions, MX proteins have been implicated in various cellular processes, including cell cycle regulation, apoptosis, and intracellular trafficking.
MX proteins are large GTPases that belong to the dynamin superfamily and typically feature:
There are two main human MX proteins:
MX proteins play significant roles in antiviral defense:
MX proteins are essential components of the innate immune response, providing broad-spectrum antiviral protection by inhibiting early stages of viral replication. They are highly inducible by type I interferons and play a critical role in controlling viral infections. Understanding the structure, function, and regulation of MX proteins can provide insights into their role in antiviral defense and potential therapeutic applications in treating viral diseases.
MX dynamin like GTPase 1 (MX1)
Interferon-induced protein p78,IFI-78K,Interferon-induced GTP-binding protein Mx1,MXA
MX dynamin like GTPase 2 ( MX2)
Myxovirus resistance protein 2,p78-related protein,MxB,Interferon-induced GTP-binding protein Mx2
MX dynamin like GTPase 3 (MX3)
Myxovirus resistance protein 3,MXB,Interferon-induced GTP-binding protein Mx3
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, CLIA Kits, ELISA Kits) relacionados con MX - Interferon-Induced GTP-Binding Protein
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 51 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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FineTest | MX1 | EH10327 | Human MX1(Myxovirus Resistance 1) ELISA Kit | human | Busacar en las instrucciones | Sandwich ELISA, Double Antibody | 0.313-20ng/ml | 96T | P20591 | RUO | ||
Abbexa | MX1 | abx495968 | Human Interferon-Induced GTP-Binding Protein Mx1 (MX1) CLIA Kit | Human | Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. | Sandwich | 1.56 ng/ml - 100 ng/ml | < 0.64 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | MX1 | abx152409 | Human Interferon-Induced GTP-Binding Protein Mx1 (MX1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 1.56 ng/ml - 100 ng/ml | < 0.65 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | MX1 | abx195798 | Human Interferon-Induced GTP-Binding Protein Mx1 (MX1) CLIA Kit | Human | Serum, plasma and other biological fluids. | 62.5 pg/ml - 4000 pg/ml | 37.5 pg/ml | 618.75 | 96 tests | RUO | ||
Abbexa | MX2 | abx495969 | Human Interferon-Induced GTP-Binding Protein Mx2 (MX2) CLIA Kit | Human | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.055 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | MX2 | abx152410 | Human Interferon-Induced GTP-Binding Protein Mx2 (MX2) ELISA Kit | Human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.07 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | MX1 | abx534075 | Mouse Interferon-induced GTP-binding protein Mx1 (MX1) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.12 ng/ml | 743.75 | 96 tests | P09922 | RUO |
Abbexa | MX2 | abx534081 | Mouse Interferon-induced GTP-binding protein Mx2 (MX2) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q9WVP9 | RUO | ||
Abbexa | MX1 | abx361172 | Pig Interferon-Induced GTP-Binding Protein Mx1 (MX1) ELISA Kit | Pig | Serum,Plasma,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | 0.19 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | MX1 | abx258950 | Rat Interferon-Induced GTP-Binding Protein Mx1 (MX1) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.12 ng/ml | 737.5 | 96 tests | P18588 | RUO |
Abbexa | MX1 | abx496584 | Rat Interferon-Induced GTP-Binding Protein Mx1 (MX1) CLIA Kit | Rat | Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.119 ng/ml | 868.75 | 96 tests | P18588 | RUO |
Abbexa | MX2 | abx534083 | Rat Interferon-Induced GTP-Binding Protein Mx2 (MX2) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P18589 | RUO | ||
Abbexa | MX3 | abx534084 | Rat Interferon-induced GTP-binding protein Mx3 (MX3) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P18590 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | MX1 | FNab05450 | anti- MX1 antibody | human | polyclonal | Rabbit | Myxovirus resistance protein 1 | IgG | Unconjugated | ELISA, WB, IHC, IP, IF | 100µg | P20591 | RUO | |
FineTest | MX1 | FNab09996 | anti- MX1 antibody | human | polyclonal | Rabbit | Myxovirus resistance protein 1 | IgG | Unconjugated | ELISA, WB, IHC | 100µg | P20591 | RUO | |
Abbexa | MX1 | abx025432 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody | Human | Monoclonal | Mouse | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Unconjugated | ELISA, WB | 281.25 | 80 µl | P20591 | RUO | |
Abbexa | MX1 | abx048492 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | MX1 | abx339617 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Unconjugated | ELISA, WB | 250 | 50 µl | P20591 | RUO | |
Abbexa | MX1 | abx102172 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Unconjugated | WB, IHC, IF/ICC | 287.5 | 100 µl | P20591 | RUO | |
Abbexa | MX1 | abx314880 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody (HRP) | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | HRP | ELISA | 162.5 | 20 µg | P20591 | RUO | |
Abbexa | MX1 | abx130433 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody Pair | Human | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | ELISA | 1462.5 | 5 × 96 tests | RUO | |||||
Abbexa | MX1 | abx025431 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody | Human | Monoclonal | Mouse | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Unconjugated | ELISA, WB | 518.75 | 100 µl | P20591 | RUO | |
Abbexa | MX1 | abx145262 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | MX1 | abx314881 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody (FITC) | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | FITC | 162.5 | 20 µg | P20591 | RUO | ||
Abbexa | MX1 | abx314882 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody (Biotin) | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Biotin | ELISA | 162.5 | 20 µg | P20591 | RUO | |
Abbexa | MX1 | abx102174 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody | Human | Monoclonal | Mouse | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Unconjugated | WB, IHC, IF/ICC | 300 | 100 µl | P20591 | RUO | |
Abbexa | MX1 | abx113971 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Unconjugated | ELISA, WB, IHC | 612.5 | 100 µl | P20591 | RUO | |
Abbexa | MX1 | abx235450 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Unconjugated | ELISA, WB, IHC, IF/ICC, IP | 350 | 100 µg | P20591 | RUO | |
Abbexa | MX1 | abx001476 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Unconjugated | WB, IHC, IF/ICC | 175 | 20 µl | P20591 | RUO | |
Abbexa | MX1 | abx317903 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Unconjugated | ELISA, WB, IHC, IF/ICC, IP | 162.5 | 20 µg | P20591 | RUO | |
Abbexa | MX1 | abx216986 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | P20591 | RUO | |
Abbexa | MX2 | abx336148 | Interferon-Induced GTP-Binding Protein Mx2 (MX2) Antibody (FITC) | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx2 (MX2) | FITC | 162.5 | 20 µg | P20592 | RUO | ||
Abbexa | MX2 | abx336147 | Interferon-Induced GTP-Binding Protein Mx2 (MX2) Antibody (HRP) | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx2 (MX2) | HRP | ELISA | 162.5 | 20 µg | P20592 | RUO | |
Abbexa | MX2 | abx323753 | Interferon-Induced GTP-Binding Protein Mx2 (MX2) Antibody | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx2 (MX2) | Unconjugated | ELISA | 187.5 | 50 µg | P20592 | RUO | |
Abbexa | MX2 | abx336149 | Interferon-Induced GTP-Binding Protein Mx2 (MX2) Antibody (Biotin) | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx2 (MX2) | Biotin | ELISA | 162.5 | 20 µg | P20592 | RUO | |
Abbexa | MX2 | abx129276 | Interferon-Induced GTP-Binding Protein Mx2 (MX2) Antibody | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx2 (MX2) | Unconjugated | WB, IHC, IF/ICC | 287.5 | 100 µl | P20592 | RUO | |
Abbexa | MX2 | abx173702 | Interferon-Induced GTP-Binding Protein Mx2 (MX2) Antibody | Human | Monoclonal | Mouse | Interferon-Induced GTP-Binding Protein Mx2 (MX2) | Unconjugated | WB, IHC, IF/ICC | 875 | 1 ml | RUO | ||
Abbexa | MX2 | abx334180 | Interferon-Induced GTP-Binding Protein Mx2 (MX2) Antibody | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx2 (MX2) | Unconjugated | ELISA, IHC, IF/ICC | 162.5 | 20 µg | P20592 | RUO | |
Abbexa | MX2 | abx015097 | Interferon-Induced GTP-Binding Protein Mx2 (MX2) Antibody | Human | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx2 (MX2) | Unconjugated | ELISA, WB | 43.75 | 10 µg | P20592 | RUO | |
Abbexa | MX1 | abx102173 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody | Mouse | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Unconjugated | WB, IHC, IF/ICC | 287.5 | 100 µl | RUO | ||
Abbexa | MX1 | abx130316 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody | Rat | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Unconjugated | WB, IHC, IF/ICC | 300 | 100 µl | P18588 | RUO | |
Abbexa | MX1 | abx102175 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody | Rat | Polyclonal | Rabbit | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | Unconjugated | WB, IHC, IF/ICC | 300 | 100 µl | P18588 | RUO | |
Abbexa | MX1 | abx370455 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody Pair | Rat | Interferon-Induced GTP-Binding Protein Mx1 (MX1) | ELISA | 1612.5 | 5 × 96 tests | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | MX1 | abx167708 | Rat Interferon-Induced GTP-Binding Protein Mx1 (MX1) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | P18588 | RUO |
Abbexa | MX1 | abx068185 | Rat Interferon-Induced GTP-Binding Protein Mx1 (MX1) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | P18588 | RUO |
Abbexa | MX1 | abx261148 | Interferon-Induced GTP-Binding Protein Mx1 (MX1) Protein | Recombinant | Unconjugated | SDS-PAGE | 225 | 5 µg | P79135 | RUO | ||
Abbexa | MX1 | abx068186 | Mouse Interferon-Induced GTP-Binding Protein Mx1 (MX1) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | P09922 | RUO |
Abbexa | MX1 | abx680373 | Human Interferon-Induced GTP-Binding Protein Mx1 (MX1) Protein | Human | Recombinant | E. coli | Unconjugated | SDS-PAGE | 225 | 5 µg | RUO | |
Abbexa | MX1 | abx068184 | Human Interferon-Induced GTP-Binding Protein Mx1 (MX1) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 200 | 10 µg | P20591 | RUO |
Abbexa | MX2 | abx261250 | Interferon-Induced GTP-Binding Protein Mx2 (MX2) Protein | Recombinant | Unconjugated | SDS-PAGE | 225 | 5 µg | P20592 | RUO | ||
Abbexa | MX2 | abx167040 | Human Interferon-Induced GTP-Binding Protein Mx2 (MX2) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | RUO |
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