Mouse Interferon-Induced GTP-Binding Protein Mx1 (MX1) Protein
Pida mas información
935106861
info@markelab.com
Precio
234€ (10 µg)
Protein MX1
proveedor
Abbexareference
abx068186Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant MX1 is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
MX dynamin-like GTPase 1 (MX1), also known as myxovirus resistance protein 1, is a key component of the innate immune response against viral infections. MX1 belongs to the dynamin family of GTPases and exhibits antiviral activity by interfering with the replication of a wide range of RNA viruses, including influenza and vesicular stomatitis viruses. MX1 exerts its effects by targeting viral nucleocapsids, preventing their transport and replication within host cells. MX1 is induced by type I interferons (IFNs), such as IFN-alpha and IFN-beta, upon viral infection. Its GTPase activity is essential for its antiviral function, facilitating conformational changes required to entrap viral components. The protein localizes to the cytoplasm and assembles into ring-like structures, further enhancing its antiviral activity. MX1 is considered a biomarker for interferon signaling and has potential applications in antiviral therapies.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Interferon-Induced GTP-Binding Protein Mx1 (MX1)
host
E. coli
conjugation
Unconjugated
form
Lyophilized Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 59.1 kDa Observed MW (SDS-PAGE): 60 kDa Concentration: Prior to lyophilization: 100 µg/ml Sequence Fragment: Gly43-Leu308 Tag: N-terminal His tag and GST tag
expression
Recombinant
purity
> 97%
buffer
Prior to lyophilization: 100 mM NaHCO<sub>3</sub>, 500 mM NaCl, pH 8.3, containing 0.01% Sarcosyl, 5% Trehalose.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
MX1
dry ice
No
availability
Shipped within 5-7 working days.
alias
Interferon-induced protein p78,IFI-78K,Interferon-induced GTP-binding protein Mx1,MXA
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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