Interferon-Induced GTP-Binding Protein Mx2 (MX2) Antibody (HRP)

Este producto es parte de MX - Interferon-Induced GTP-Binding Protein
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169€ (20 µg)

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935106861
info@markelab.com
name
Interferon-Induced GTP-Binding Protein Mx2 (MX2) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx336147
tested applications
ELISA

Description

MX2 Antibody (HRP) is a Rabbit Polyclonal against MX2.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Interferon-Induced GTP-Binding Protein Mx2 (MX2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
HRP
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P20592
Gene ID
4600
Alias
Myxovirus resistance protein 2,p78-related protein,MxB,Interferon-induced GTP-binding protein Mx2
Background
Antibody anti-MX2
Status
RUO

Descripción

MX dynamin-like GTPase 2 (MX2) is closely related to MX1 and shares structural and functional similarities, although it has distinct antiviral properties. Unlike MX1, MX2 primarily targets retroviruses, including human immunodeficiency virus type 1 (HIV-1), by inhibiting the nuclear import of viral DNA. MX2 is also induced by type I interferons and requires GTPase activity for its antiviral function. Recent studies have shown that MX2 interacts with nuclear pore complex components to block the integration of viral DNA into the host genome. The protein plays a crucial role in the host defense mechanism, particularly in restricting lentiviral infections. MX2 is being explored as a therapeutic target for HIV and other retroviral diseases due to its selective antiviral activity and ability to modulate host-pathogen interactions.

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