Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody
312€ (100 µl)
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935106861
info@markelab.com
name
Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx102174
tested applications
WB, IHC
Description
Interferon-Induced GTP-Binding Protein MX1 (MX1) Antibody is a Mouse monoclonal against Interferon-Induced GTP-Binding Protein MX1 (MX1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Interferon-Induced GTP-Binding Protein Mx1 (MX1) Immunogen: abx068184 - Recombinant Human MX1 (Ser80-Leu342) expressed in E. coli. |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-30 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2b Kappa |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P20591 |
| Alias | Interferon-induced protein p78,IFI-78K,Interferon-induced GTP-binding protein Mx1,MXA |
| Background | Antibody anti-MX1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
MX dynamin-like GTPase 1 (MX1), also known as myxovirus resistance protein 1, is a key component of the innate immune response against viral infections. MX1 belongs to the dynamin family of GTPases and exhibits antiviral activity by interfering with the replication of a wide range of RNA viruses, including influenza and vesicular stomatitis viruses. MX1 exerts its effects by targeting viral nucleocapsids, preventing their transport and replication within host cells. MX1 is induced by type I interferons (IFNs), such as IFN-alpha and IFN-beta, upon viral infection. Its GTPase activity is essential for its antiviral function, facilitating conformational changes required to entrap viral components. The protein localizes to the cytoplasm and assembles into ring-like structures, further enhancing its antiviral activity. MX1 is considered a biomarker for interferon signaling and has potential applications in antiviral therapies.
Related Products
Human Interferon-Induced GTP-Binding Protein Mx1 (MX1) Protein
Human MX1 Protein is a recombinant Human protein expressed in E. coli.
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