Rat Interferon-Induced GTP-Binding Protein Mx2 (MX2) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for MX2
proveedor
Abbexareference
abx534083Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Interferon-Induced GTP-Binding Protein Mx2 (MX2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Interferon-induced GTP-binding protein Mx2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
MX dynamin-like GTPase 2 (MX2) is closely related to MX1 and shares structural and functional similarities, although it has distinct antiviral properties. Unlike MX1, MX2 primarily targets retroviruses, including human immunodeficiency virus type 1 (HIV-1), by inhibiting the nuclear import of viral DNA. MX2 is also induced by type I interferons and requires GTPase activity for its antiviral function. Recent studies have shown that MX2 interacts with nuclear pore complex components to block the integration of viral DNA into the host genome. The protein plays a crucial role in the host defense mechanism, particularly in restricting lentiviral infections. MX2 is being explored as a therapeutic target for HIV and other retroviral diseases due to its selective antiviral activity and ability to modulate host-pathogen interactions.
Características del producto
category
ELISA Kits
immunogen target
Interferon-Induced GTP-Binding Protein Mx2 (MX2)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
Myxovirus resistance protein 2,p78-related protein,MxB,Interferon-induced GTP-binding protein Mx2
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
MX2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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