Rat Interferon-Induced GTP-Binding Protein Mx2 (MX2) ELISA Kit

Este producto es parte de MX - Interferon-Induced GTP-Binding Protein
Rat Interferon-Induced GTP-Binding Protein Mx2 (MX2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for MX2

proveedor

Abbexa

reference

abx534083

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Interferon-Induced GTP-Binding Protein Mx2 (MX2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Interferon-induced GTP-binding protein Mx2 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

MX dynamin-like GTPase 2 (MX2) is closely related to MX1 and shares structural and functional similarities, although it has distinct antiviral properties. Unlike MX1, MX2 primarily targets retroviruses, including human immunodeficiency virus type 1 (HIV-1), by inhibiting the nuclear import of viral DNA. MX2 is also induced by type I interferons and requires GTPase activity for its antiviral function. Recent studies have shown that MX2 interacts with nuclear pore complex components to block the integration of viral DNA into the host genome. The protein plays a crucial role in the host defense mechanism, particularly in restricting lentiviral infections. MX2 is being explored as a therapeutic target for HIV and other retroviral diseases due to its selective antiviral activity and ability to modulate host-pathogen interactions.

Características del producto

category

ELISA Kits


immunogen target

Interferon-Induced GTP-Binding Protein Mx2 (MX2)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

Myxovirus resistance protein 2,p78-related protein,MxB,Interferon-induced GTP-binding protein Mx2


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

MX2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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