Rat Interferon-Induced GTP-Binding Protein Mx2 (MX2) ELISA Kit

Este producto es parte de MX - Interferon-Induced GTP-Binding Protein
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715€ (96 tests)

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935106861
info@markelab.com
name
Rat Interferon-Induced GTP-Binding Protein Mx2 (MX2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx534083
tested applications
ELISA

Description

Rat Interferon-Induced GTP-Binding Protein Mx2 (MX2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Interferon-induced GTP-binding protein Mx2 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Interferon-Induced GTP-Binding Protein Mx2 (MX2)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P18589
Alias
Myxovirus resistance protein 2,p78-related protein,MxB,Interferon-induced GTP-binding protein Mx2
Background
Elisa kits for MX2
Status
RUO
Note
Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

MX dynamin-like GTPase 2 (MX2) is closely related to MX1 and shares structural and functional similarities, although it has distinct antiviral properties. Unlike MX1, MX2 primarily targets retroviruses, including human immunodeficiency virus type 1 (HIV-1), by inhibiting the nuclear import of viral DNA. MX2 is also induced by type I interferons and requires GTPase activity for its antiviral function. Recent studies have shown that MX2 interacts with nuclear pore complex components to block the integration of viral DNA into the host genome. The protein plays a crucial role in the host defense mechanism, particularly in restricting lentiviral infections. MX2 is being explored as a therapeutic target for HIV and other retroviral diseases due to its selective antiviral activity and ability to modulate host-pathogen interactions.

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