Rat Interferon-Induced GTP-Binding Protein Mx1 (MX1) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
767€ (96 tests)
Elisa kits for MX1
proveedor
Abbexareference
abx258950Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Interferon-Induced GTP-Binding Protein Mx1 (MX1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Interferon-Induced GTP-Binding Protein Mx1 (MX1) concentrations in tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Background
MX dynamin-like GTPase 1 (MX1), also known as myxovirus resistance protein 1, is a key component of the innate immune response against viral infections. MX1 belongs to the dynamin family of GTPases and exhibits antiviral activity by interfering with the replication of a wide range of RNA viruses, including influenza and vesicular stomatitis viruses. MX1 exerts its effects by targeting viral nucleocapsids, preventing their transport and replication within host cells. MX1 is induced by type I interferons (IFNs), such as IFN-alpha and IFN-beta, upon viral infection. Its GTPase activity is essential for its antiviral function, facilitating conformational changes required to entrap viral components. The protein localizes to the cytoplasm and assembles into ring-like structures, further enhancing its antiviral activity. MX1 is considered a biomarker for interferon signaling and has potential applications in antiviral therapies.
Características del producto
category
ELISA Kits
immunogen target
Interferon-Induced GTP-Binding Protein Mx1 (MX1)
reactivity
Rat
test range
0.312 ng/ml - 20 ng/ml
sensitivity
< 0.12 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
Interferon-induced protein p78,IFI-78K,Interferon-induced GTP-binding protein Mx1,MXA
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
MX1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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