Human Interferon-Induced GTP-Binding Protein Mx1 (MX1) CLIA Kit

Este producto es parte de MX - Interferon-Induced GTP-Binding Protein
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643.5€ (96 tests)

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935106861
info@markelab.com
name
Human Interferon-Induced GTP-Binding Protein Mx1 (MX1) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx195798
tested applications
CLIA

Description

Human Myxovirus Resistance 1 (MX1) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Myxovirus Resistance 1 (MX1).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
CLIA Kits
Immunogen Target
Interferon-Induced GTP-Binding Protein Mx1 (MX1)
Reactivity
Human
Detection Method
Chemiluminescent
Assay Data
Quantitative
Test Range
62.5 pg/ml - 4000 pg/ml
Sensitivity
37.5 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
CLIA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-12 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
Interferon-induced protein p78,IFI-78K,Interferon-induced GTP-binding protein Mx1,MXA
Background
CLIA Kits MX1
Status
RUO
Note
The validity for this kit is 6 months.   This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

MX dynamin-like GTPase 1 (MX1), also known as myxovirus resistance protein 1, is a key component of the innate immune response against viral infections. MX1 belongs to the dynamin family of GTPases and exhibits antiviral activity by interfering with the replication of a wide range of RNA viruses, including influenza and vesicular stomatitis viruses. MX1 exerts its effects by targeting viral nucleocapsids, preventing their transport and replication within host cells. MX1 is induced by type I interferons (IFNs), such as IFN-alpha and IFN-beta, upon viral infection. Its GTPase activity is essential for its antiviral function, facilitating conformational changes required to entrap viral components. The protein localizes to the cytoplasm and assembles into ring-like structures, further enhancing its antiviral activity. MX1 is considered a biomarker for interferon signaling and has potential applications in antiviral therapies.

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