Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody
637€ (100 µl)
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Name
Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx113971
Tested Applications
ELISA, WB, IHC
Description
Myxovirus (Influenza Virus) Resistance 1, Interferon-Inducible Protein P78 (Mouse) Antibody is a Rabbit Polyclonal antibody against Myxovirus (Influenza Virus) Resistance 1, Interferon-Inducible Protein P78 (Mouse).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Interferon-Induced GTP-Binding Protein Mx1 (MX1) Immunogen: Human MX1. |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P20591 |
| Gene ID | 4599 |
| NCBI Accession | NP_001138397.1, NM_001144925.2 |
| OMIM | 147150 |
| Alias | Interferon-induced protein p78,IFI-78K,Interferon-induced GTP-binding protein Mx1,MXA |
| Background | Antibody anti-MX1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
MX dynamin-like GTPase 1 (MX1), also known as myxovirus resistance protein 1, is a key component of the innate immune response against viral infections. MX1 belongs to the dynamin family of GTPases and exhibits antiviral activity by interfering with the replication of a wide range of RNA viruses, including influenza and vesicular stomatitis viruses. MX1 exerts its effects by targeting viral nucleocapsids, preventing their transport and replication within host cells. MX1 is induced by type I interferons (IFNs), such as IFN-alpha and IFN-beta, upon viral infection. Its GTPase activity is essential for its antiviral function, facilitating conformational changes required to entrap viral components. The protein localizes to the cytoplasm and assembles into ring-like structures, further enhancing its antiviral activity. MX1 is considered a biomarker for interferon signaling and has potential applications in antiviral therapies.
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