Family main features
The Histamine Receptor H (HRH) refers to a family of G protein-coupled receptors (GPCRs) that mediate the effects of histamine, a biogenic amine neurotransmitter and immunomodulator. Histamine receptors are classified into four subtypes: H1R, H2R, H3R, and H4R. Histamine receptors were identified and classified based on their distinct pharmacological properties and tissue distributions.Histamine is a signaling molecule involved in various physiological processes, including inflammation, allergic responses, neurotransmission, and gastric acid secretion. Each subtype also interacts with specific synthetic ligands and drugs that can selectively activate or inhibit their activity. In summary, histamine receptors play diverse roles in modulating physiological processes throughout the body, including allergic responses, gastric acid secretion, neurotransmission, and immune function
· Transmembrane Protein: Histamine receptors are seven-transmembrane domain receptors, characteristic of GPCRs.
· Topology: They consist of an extracellular N-terminus, seven transmembrane helices connected by intracellular and extracellular loops, and an intracellular C-terminus.
· Binding Sites: Each subtype has a specific binding site for histamine and other ligands.
1. H1R (HRH1): Expressed in smooth muscle, endothelial cells, and neurons. Involved in allergic responses, vasodilation, bronchoconstriction, and CNS effects.
2. H2R (HRH2): Predominantly found in gastric parietal cells, cardiac muscle, and mast cells. Regulates gastric acid secretion, cardiac contractility, and immune responses.
3. H3R (HRH3): Primarily located in the central nervous system (CNS), particularly in presynaptic neurons. Modulates neurotransmitter release, sleep-wake cycle, cognition, and appetite.
4. H4R (HRH4): Found in immune cells, especially mast cells, eosinophils, and dendritic cells. Regulates immune cell chemotaxis, cytokine release, and inflammatory responses.
Drug Development: Histamine receptor ligands are actively investigated for their therapeutic potential in various diseases, including allergy, gastric disorders, neurological conditions, and inflammatory diseases.
histamine receptor H1 (HRH1)
HRH1,H1R,HH1R,Hisr,H1-R,hisH1
histamine receptor H2 (HRH2)
HRH2,gastric receptor I,H2R,HH2R
histamine receptor H3 (HRH3)
HRH3,GPCR97,H3R,HH3R
histamine receptor H4 (HRH4)
HRH4,GPCR105,HH4R,H4R,AXOR35, BG26,GPRv53
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, ELISA Kits, Primary Antibodies, CLIA Kits) relacionados con HRH - histamine receptor H
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 77 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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FineTest | HRH1 | EH4952 | Human HRH1 (Histamine H1 receptor) ELISA kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 31.25-2000pg/ml | 96T | P35367 | RUO | ||
FineTest | HRH2 | EH4953 | Human HRH2 (Histamine H2 receptor)ELISA kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 31.25-2000pg/ml | 96T | P25021 | RUO | ||
FineTest | HRH4 | EH4045 | Human HRH4(Histamine Receptor H4) ELISA Kit | human | Busacar en las instrucciones | Sandwich ELISA, Double Antibody | 0.156-10ng/ml | 96T | Q9H3N8 | RUO | ||
Abbexa | HRH1 | abx151811 | Human Histamine Receptor H1 (HRH1) ELISA Kit | Human | Tissue homogenates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.13 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | HRH1 | abx595295 | Human Histamine Receptor H1 (HRH1) Cell ELISA Kit | Human | Cell ELISA | 493.75 | 96 tests | P35367 | RUO | |||
Abbexa | HRH1 | abx495091 | Human Histamine Receptor H1 (HRH1) CLIA Kit | Human | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.114 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | HRH2 | abx387883 | Human Histamine H2 Receptor (HRH2) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | P25021 | RUO |
Abbexa | HRH3 | abx527441 | Human Histamine H3 Receptor (HRH3) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q9Y5N1 | RUO | ||
Abbexa | HRH4 | abx495094 | Human Histamine H4 Receptor (HRH4) CLIA Kit | Human | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.056 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | HRH4 | abx151812 | Human Histamine H4 Receptor (HRH4) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Competitive | 246.9 pg/ml - 20000 pg/ml | < 85.2 pg/ml | 687.5 | 96 tests | RUO | |
Abbexa | HRH1 | abx527435 | Mouse Histamine H1 receptor (HRH1) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P70174 | RUO | ||
Abbexa | HRH2 | abx527439 | Mouse Histamine H2 receptor (HRH2) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P97292 | RUO | ||
Abbexa | HRH3 | abx527442 | Mouse Histamine H3 Receptor (HRH3) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P58406 | RUO | ||
Abbexa | HRH4 | abx154142 | Mouse Histamine H4 Receptor (HRH4) ELISA Kit | Mouse | Tissue homogenates,Other biological fluids | Competitive | 246.9 pg/ml - 20000 pg/ml | < 92.4 pg/ml | 687.5 | 96 tests | RUO | |
Abbexa | HRH4 | abx570937 | Mouse Histamine H4 Receptor (HRH4) ELISA Kit | Mouse | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.78 ng/ml - 50 ng/ml | < 0.2 ng/ml | 618.75 | 96 tests | Q91ZY2 | RUO |
Abbexa | HRH4 | abx495095 | Mouse Histamine H4 Receptor (HRH4) CLIA Kit | Mouse | Tissue homogenates and other biological fluids. | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.051 ng/ml | 812.5 | 96 tests | RUO | |
FineTest | HRH1 | ER1072 | Rat HRH1(Histamine Receptor H1) ELISA Kit | rat | Busacar en las instrucciones | Sandwich ELISA, Double Antibody | 15.625-1000pg/ml | 96T | P31390 | RUO | ||
FineTest | HRH4 | ER1047 | Rat HRH4(Histamine Receptor H4) ELISA Kit | rat | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.313-20ng/ml | 96T | Q91ZY1 | RUO | ||
Abbexa | HRH1 | abx495092 | Rat Histamine Receptor H1 (HRH1) CLIA Kit | Rat | Tissue homogenates and other biological fluids. | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.067 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | HRH1 | abx155634 | Rat Histamine Receptor H1 (HRH1) ELISA Kit | Rat | Tissue homogenates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.07 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | HRH2 | abx527440 | Rat Histamine H2 Receptor (HRH2) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P25102 | RUO | ||
Abbexa | HRH3 | abx155635 | Rat Histamine H3 Receptor (HRH3) ELISA Kit | Rat | Tissue homogenates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.13 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | HRH3 | abx495093 | Rat Histamine H3 Receptor (HRH3) CLIA Kit | Rat | Tissue homogenates and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.124 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | HRH4 | abx155636 | Rat Histamine H4 Receptor (HRH4) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.06 ng/ml | 662.5 | 96 tests | RUO | |
Abbexa | HRH4 | abx255718 | Rat Histamine H4 Receptor (HRH4) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | 0.19 ng/ml | 562.5 | 96 tests | Q91ZY1 | RUO |
Abbexa | HRH4 | abx495096 | Rat Histamine H4 Receptor (HRH4) CLIA Kit | Rat | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.055 ng/ml | 812.5 | 96 tests | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | HRH3 | abx432247 | Histamine H3 Receptor (HRH3) Antibody | Polyclonal | Goat | Histamine H3 Receptor (HRH3) | Unconjugated | P-ELISA | 250 | 200 µl | RUO | |||
FineTest | HRH1 | FNab04010 | anti- HRH1 antibody | human | polyclonal | Rabbit | histamine receptor H1 | IgG | Unconjugated | ELISA, WB, IHC | 100µg | P35367 | RUO | |
FineTest | HRH2 | FNab04011 | anti- HRH2 antibody | human | polyclonal | Rabbit | histamine receptor H2 | IgG | Unconjugated | ELISA, WB | 100µg | P25021 | RUO | |
Abbexa | HRH1 | abx316947 | Histamine Receptor H1 (HRH1) Antibody (HRP) | Human | Polyclonal | Rabbit | Histamine Receptor H1 (HRH1) | HRP | ELISA | 162.5 | 20 µg | P35367 | RUO | |
Abbexa | HRH1 | abx339310 | Histamine Receptor H1 (HRH1) Antibody | Human | Polyclonal | Rabbit | Histamine Receptor H1 (HRH1) | Unconjugated | ELISA, IHC | 250 | 50 µl | P35367 | RUO | |
Abbexa | HRH1 | abx316949 | Histamine Receptor H1 (HRH1) Antibody (Biotin) | Human | Polyclonal | Rabbit | Histamine Receptor H1 (HRH1) | Biotin | ELISA | 162.5 | 20 µg | P35367 | RUO | |
Abbexa | HRH1 | abx316948 | Histamine Receptor H1 (HRH1) Antibody (FITC) | Human | Polyclonal | Rabbit | Histamine Receptor H1 (HRH1) | FITC | 162.5 | 20 µg | P35367 | RUO | ||
Abbexa | HRH1 | abx324148 | Histamine Receptor H1 (HRH1) Antibody | Human | Polyclonal | Rabbit | Histamine Receptor H1 (HRH1) | Unconjugated | ELISA, WB, IF/ICC | 187.5 | 50 µg | P35367 | RUO | |
Abbexa | HRH1 | abx211277 | Histamine Receptor H1 (HRH1) Antibody | Human | Polyclonal | Rabbit | Histamine Receptor H1 (HRH1) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | P35367 | RUO | |
Abbexa | HRH1 | abx028046 | Histamine Receptor H1 (HRH1) Antibody | Human | Polyclonal | Rabbit | Histamine Receptor H1 (HRH1) | Unconjugated | ELISA, WB, IHC | 250 | 80 µl | P35367 | RUO | |
Abbexa | HRH1 | abx432795 | Histamine Receptor H1 (HRH1) Antibody | Human | Polyclonal | Goat | Histamine Receptor H1 (HRH1) | Unconjugated | P-ELISA, WB, IHC | 387.5 | 200 µl | RUO | ||
Abbexa | HRH1 | abx302358 | Histamine Receptor H1 (HRH1) Antibody | Human | Polyclonal | Rabbit | Histamine Receptor H1 (HRH1) | Unconjugated | ELISA, WB, IHC, IF/ICC | 162.5 | 20 µg | P35367 | RUO | |
Abbexa | HRH1 | abx001230 | Histamine Receptor H1 (HRH1) Antibody | Human | Polyclonal | Rabbit | Histamine Receptor H1 (HRH1) | Unconjugated | WB | 175 | 20 µl | P35367 | RUO | |
Abbexa | HRH1 | abx332952 | HRH1 (pS398) Antibody | Human | Polyclonal | Rabbit | HRH1 (pS398) | Unconjugated | ELISA, IF/ICC | 412.5 | 100 µl | P35367 | RUO | |
Abbexa | HRH1 | abx234010 | Histamine Receptor H1 (HRH1) Antibody | Human | Polyclonal | Rabbit | Histamine Receptor H1 (HRH1) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | P35367 | RUO | |
Abbexa | HRH1 | abx326349 | Histamine Receptor H1 Phospho-Ser398 (HRH1 pS398) Antibody | Human | Polyclonal | Rabbit | Histamine Receptor H1 Phospho-Ser398 (HRH1 pS398) | Unconjugated | ELISA, IF/ICC | 187.5 | 50 µg | P35367 | RUO | |
Abbexa | HRH1 | abx113018 | Histamine Receptor H1 (HRH1) Antibody | Human | Polyclonal | Rabbit | Histamine Receptor H1 (HRH1) | Unconjugated | ELISA, WB, IHC | 612.5 | 100 µl | P35367 | RUO | |
Abbexa | HRH1 | abx012490 | Histamine H1 Receptor (Phospho-Ser398) Antibody | Human | Polyclonal | Rabbit | Histamine H1 Receptor | Unconjugated | ELISA, IF/ICC | 43.75 | 10 µg | P35367 | RUO | |
Abbexa | HRH1 | abx431337 | Histamine Receptor H1 (HRH1) Antibody | Human | Polyclonal | Goat | Histamine Receptor H1 (HRH1) | Unconjugated | P-ELISA, IHC, IF/ICC, FCM | 387.5 | 200 µl | RUO | ||
Abbexa | HRH2 | abx211356 | Histamine H2 Receptor (HRH2) Antibody | Human | Polyclonal | Rabbit | Histamine H2 Receptor (HRH2) | Unconjugated | ELISA, WB | 250 | 50 µl | P25021 | RUO | |
Abbexa | HRH2 | abx028457 | Histamine H2 Receptor (HRH2) Antibody | Human | Polyclonal | Rabbit | Histamine H2 Receptor (HRH2) | Unconjugated | ELISA, WB | 250 | 80 µl | P25021 | RUO | |
Abbexa | HRH2 | abx324359 | Histamine H2 Receptor (HRH2) Antibody | Human | Polyclonal | Rabbit | Histamine H2 Receptor (HRH2) | Unconjugated | ELISA, WB, IF/ICC | 187.5 | 50 µg | P25021 | RUO | |
Abbexa | HRH2 | abx211355 | Histamine H2 Receptor (HRH2) Antibody | Human | Polyclonal | Rabbit | Histamine H2 Receptor (HRH2) | Unconjugated | ELISA, WB | 250 | 50 µl | P25021 | RUO | |
Abbexa | HRH2 | abx113019 | Histamine H2 Receptor (HRH2) Antibody | Human | Polyclonal | Rabbit | Histamine H2 Receptor (HRH2) | Unconjugated | ELISA, WB | 612.5 | 100 µl | P25021 | RUO | |
Abbexa | HRH2 | abx234011 | Histamine H2 Receptor (HRH2) Antibody | Human | Polyclonal | Rabbit | Histamine H2 Receptor (HRH2) | Unconjugated | ELISA, WB | 350 | 100 µg | P25021 | RUO | |
Abbexa | HRH3 | abx315556 | Histamine H3 Receptor (HRH3) Antibody (HRP) | Human | Polyclonal | Rabbit | Histamine H3 Receptor (HRH3) | HRP | ELISA | 162.5 | 20 µg | Q9Y5N1 | RUO | |
Abbexa | HRH3 | abx432246 | Histamine H3 receptor Antibody | Human | Polyclonal | Goat | Histamine H3 receptor | Unconjugated | P-ELISA, WB, IHC | 387.5 | 200 µl | RUO | ||
Abbexa | HRH3 | abx210971 | Histamine H3 Receptor (HRH3) Antibody | Human | Polyclonal | Rabbit | Histamine H3 Receptor (HRH3) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q9Y5N1 | RUO | |
Abbexa | HRH3 | abx315558 | Histamine H3 Receptor (HRH3) Antibody (Biotin) | Human | Polyclonal | Rabbit | Histamine H3 Receptor (HRH3) | Biotin | ELISA | 162.5 | 20 µg | Q9Y5N1 | RUO | |
Abbexa | HRH3 | abx315557 | Histamine H3 Receptor (HRH3) Antibody (FITC) | Human | Polyclonal | Rabbit | Histamine H3 Receptor (HRH3) | FITC | 162.5 | 20 µg | Q9Y5N1 | RUO | ||
Abbexa | HRH3 | abx302577 | Histamine H3 Receptor (HRH3) Antibody | Human | Polyclonal | Rabbit | Histamine H3 Receptor (HRH3) | Unconjugated | ELISA, WB, IHC, IF/ICC | 162.5 | 20 µg | Q9Y5N1 | RUO | |
Abbexa | HRH3 | abx402389 | Histamine H3 Receptor (HRH3) Antibody | Human | Monoclonal | Rabbit | Histamine H3 Receptor (HRH3) | Unconjugated | ELISA, FCM | 287.5 | 50 µl | Q9Y5N1 | RUO | |
Abbexa | HRH3 | abx212517 | Histamine H3 Receptor (HRH3) Antibody | Human | Polyclonal | Rabbit | Histamine H3 Receptor (HRH3) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | Q9Y5N1 | RUO | |
Abbexa | HRH3 | abx329659 | Histamine H3 Receptor (HRH3) Antibody | Human | Polyclonal | Rabbit | Histamine H3 Receptor (HRH3) | Unconjugated | ELISA, WB, IHC, IF/ICC | 187.5 | 50 µg | Q9Y5N1 | RUO | |
Abbexa | HRH4 | abx176847 | Histamine H4 Receptor (HRH4) Antibody | Human | Polyclonal | Rabbit | Histamine H4 Receptor (HRH4) | Unconjugated | WB, IHC, IF/ICC | 750 | 1 ml | RUO | ||
Abbexa | HRH4 | abx172818 | Histamine H4 Receptor (HRH4) Antibody | Human | Monoclonal | Mouse | Histamine H4 Receptor (HRH4) | Unconjugated | WB, IHC, IF/ICC | 787.5 | 1 ml | RUO | ||
Abbexa | HRH4 | abx335958 | Histamine H4 Receptor (HRH4) Antibody (HRP) | Human | Polyclonal | Rabbit | Histamine H4 Receptor (HRH4) | HRP | ELISA | 162.5 | 20 µg | Q9H3N8 | RUO | |
Abbexa | HRH4 | abx335959 | Histamine H4 Receptor (HRH4) Antibody (FITC) | Human | Polyclonal | Rabbit | Histamine H4 Receptor (HRH4) | FITC | 162.5 | 20 µg | Q9H3N8 | RUO | ||
Abbexa | HRH4 | abx249477 | Histamine H4 Receptor (HRH4) Antibody | Human | Polyclonal | Rabbit | Histamine H4 Receptor (HRH4) | Unconjugated | ELISA, IF/ICC | 43.75 | 10 µg | Q9H3N8 | RUO | |
Abbexa | HRH4 | abx324360 | Histamine H4 Receptor (HRH4) Antibody | Human | Polyclonal | Rabbit | Histamine H4 Receptor (HRH4) | Unconjugated | ELISA, WB, IF/ICC | 187.5 | 50 µg | Q9H3N8 | RUO | |
Abbexa | HRH4 | abx335960 | Histamine H4 Receptor (HRH4) Antibody (Biotin) | Human | Polyclonal | Rabbit | Histamine H4 Receptor (HRH4) | Biotin | ELISA | 162.5 | 20 µg | Q9H3N8 | RUO | |
Abbexa | HRH4 | abx338774 | Histamine H4 Receptor (HRH4) Antibody | Human | Polyclonal | Rabbit | Histamine H4 Receptor (HRH4) | Unconjugated | ELISA, WB, IHC, IF/ICC | 162.5 | 20 µg | Q9H3N8 | RUO | |
Abbexa | HRH4 | abx136061 | Histamine H4 Receptor (HRH4) Antibody | Human | Polyclonal | Rabbit | Histamine H4 Receptor (HRH4) | Unconjugated | WB | 175 | 20 µl | Q9H3N8 | RUO | |
Abbexa | HRH4 | abx176848 | Histamine H4 Receptor (HRH4) Antibody | Mouse | Polyclonal | Rabbit | Histamine H4 Receptor (HRH4) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | HRH1 | P8206 | Recombinant Human HRH1 | Human | Recombinant | E.Coli | Western Blot, ELISA | 50μg | P35367 | RUO | ||
Abbexa | HRH1 | abx653747 | Rat Histamine Receptor H1 (HRH1) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 1800 | 1 mg | RUO | |
Abbexa | HRH1 | abx653746 | Human Histamine Receptor H1 (HRH1) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 1800 | 1 mg | RUO | |
Abbexa | HRH3 | abx653748 | Rat Histamine H3 Receptor (HRH3) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 1800 | 1 mg | RUO | |
Abbexa | HRH4 | abx653749 | Human Histamine H4 Receptor (HRH4) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 200 | 10 µg | RUO | |
Abbexa | HRH4 | abx653750 | Mouse Histamine H4 Receptor (HRH4) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 1800 | 1 mg | RUO | |
Abbexa | HRH4 | abx653752 | Rat Histamine H4 Receptor (HRH4) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 1800 | 1 mg | RUO |
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