Family main features
CD79A, also known as Ig-alpha, is a protein encoded by the CD79A gene in humans. It is a crucial component of the B cell receptor (BCR) complex, playing a significant role in B cell development, activation, and signaling. The BCR complex is essential for the adaptive immune response, allowing B cells to recognize and respond to specific antigens. CD79A, along with CD79B (Ig-beta), forms the signaling component of the BCR, transmitting signals from the antigen-bound surface immunoglobulin (Ig) to the cell's interior, initiating a cascade of intracellular events leading to B cell activation, proliferation, and differentiation.
CD79A is a transmembrane protein comprising 226 amino acids. It has several distinct structural features:
CD79A is classified as a member of the immunoglobulin superfamily and is one of the two components of the BCR complex, the other being CD79B. There are no known subtypes of CD79A, but it works in conjunction with CD79B to perform its functions within the BCR complex.
B Cell Development:
Antigen Recognition and Signal Transduction:
B Cell Activation and Proliferation:
Role in Immune Responses:
Immunodeficiencies:
Autoimmune Diseases:
Lymphomas and Leukemias:
Therapeutic Targeting:
CD79A is a critical component of the B cell receptor complex, essential for B cell development, activation, and signaling. Its structure comprises an extracellular domain for antigen binding, a transmembrane domain for complex formation, and an intracellular domain with ITAMs for signal transduction. CD79A plays a pivotal role in immune responses, both T cell-dependent and T cell-independent, and is implicated in various clinical conditions, including immunodeficiencies, autoimmune diseases, and B cell malignancies. Understanding the molecular mechanisms of CD79A and its role in B cell biology provides valuable insights for the development of targeted therapies for these conditions.
CD79a molecule (CD79A)
IGA,MB1,MB-1,IGAlpha,Ig-alpha,MB-1 membrane glycoprotein,Membrane-bound immunoglobulin-associated protein,Surface IgM-associated protein,B-cell antigen receptor complex-associated protein alpha chain
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits) relacionados con CD79A molecule
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Esta página contiene 41 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | CD79A | abx386399 | Human B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) ELISA Kit | Human | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 1.56 ng/ml - 100 ng/ml | < 0.63 ng/ml | 687.5 | 96 tests | P11912 | RUO |
Abbexa | CD79A | abx505804 | Mouse B-cell antigen receptor complex-associated protein alpha chain (CD79A) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P11911 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | CD79A | FNab01499 | anti- CD79A antibody | human | polyclonal | Rabbit | CD79a molecule, immunoglobulin-associated alpha | IgG | Unconjugated | ELISA, WB, IHC | 100µg | P11912 | RUO | |
FineTest | CD79A | FNab10737 | anti- CD79A antibody | human | polyclonal | Rabbit | CD79a molecule, immunoglobulin-associated alpha | IgG | Unconjugated | ELISA, WB, IHC | 100µg | P11912 | RUO | |
Abbexa | CD79A | abx347143 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (PE) | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | PE | FCM | 400 | 100 tests | P11912 | RUO | |
Abbexa | CD79A | abx315624 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (FITC) | Human | Polyclonal | Rabbit | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | FITC | 162.5 | 20 µg | P11912 | RUO | ||
Abbexa | CD79A | abx302243 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Polyclonal | Rabbit | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, IHC, IF/ICC | 162.5 | 20 µg | P11912 | RUO | |
Abbexa | CD79A | abx412925 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, IHC, FCM, IP | 550 | 200 µg | P11912 | RUO | |
Abbexa | CD79A | abx015183 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Polyclonal | Rabbit | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, WB | 43.75 | 10 µg | P11912 | RUO | |
Abbexa | CD79A | abx414328 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (PE) | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | PE | FCM | 212.5 | 25 tests | P11912 | RUO | |
Abbexa | CD79A | abx027180 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Polyclonal | Rabbit | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, WB | 250 | 80 µl | P11912 | RUO | |
Abbexa | CD79A | abx028431 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Polyclonal | Rabbit | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, WB | 250 | 80 µl | P11912 | RUO | |
Abbexa | CD79A | abx414324 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (FITC) | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | FITC | FCM | 400 | 100 µg | P11912 | RUO | |
Abbexa | CD79A | abx412926 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (FITC) | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | FITC | FCM | 475 | 100 µg | P11912 | RUO | |
Abbexa | CD79A | abx315623 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (HRP) | Human | Polyclonal | Rabbit | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | HRP | ELISA | 162.5 | 20 µg | P11912 | RUO | |
Abbexa | CD79A | abx231499 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Polyclonal | Rabbit | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | P11912 | RUO | |
Abbexa | CD79A | abx315625 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (Biotin) | Human | Polyclonal | Rabbit | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Biotin | ELISA | 162.5 | 20 µg | P11912 | RUO | |
Abbexa | CD79A | abx414326 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, WB, IHC | 562.5 | 1 ml | P11912 | RUO | |
Abbexa | CD79A | abx347123 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | ELISA, IHC-P, IF/ICC, FCM, IP | 287.5 | 0.1 mg | P11912 | RUO | ||||
Abbexa | CD79A | abx414329 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, WB, IHC | 175 | 25 µg | P11912 | RUO | |
Abbexa | CD79A | abx323679 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Polyclonal | Rabbit | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, WB | 187.5 | 50 µg | P11912 | RUO | |
Abbexa | CD79A | abx347140 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (APC) | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | APC | FCM | 400 | 100 tests | P11912 | RUO | |
Abbexa | CD79A | abx341147 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, IHC | 250 | 50 µl | P11912 | RUO | |
Abbexa | CD79A | abx139335 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (APC) | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | APC | FCM | 400 | 100 tests | P11912 | RUO | |
Abbexa | CD79A | abx139329 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | WB, IHC-P, FCM, IP | 287.5 | 0.1 mg | P11912 | RUO | |
Abbexa | CD79A | abx139334 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (PE) | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | PE | FCM | 400 | 100 tests | P11912 | RUO | |
Abbexa | CD79A | abx019052 | CD79 alpha Antibody | Human | Polyclonal | Rabbit | CD79 alpha | Unconjugated | WB, IF/ICC | 300 | 100 µg | P11912 | RUO | |
Abbexa | CD79A | abx213531 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Polyclonal | Rabbit | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, WB | 250 | 50 µl | P11912 | RUO | |
Abbexa | CD79A | abx325398 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Polyclonal | Rabbit | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, WB | 187.5 | 50 µg | P11912 | RUO | |
Abbexa | CD79A | abx213530 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Polyclonal | Rabbit | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, WB | 250 | 50 µl | P11912 | RUO | |
Abbexa | CD79A | abx148556 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Polyclonal | Rabbit | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | P11912 | RUO | |
Abbexa | CD79A | abx005604 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Polyclonal | Rabbit | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | WB, IHC, IF/ICC | 175 | 20 µl | P11912 | RUO | |
Abbexa | CD79A | abx347016 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (APC / Cyanine 7) | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | APC / Cyanine 7 | FCM | 437.5 | 100 tests | P11912 | RUO | |
Abbexa | CD79A | abx347120 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (PerCP / Cyanine 5.5) | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | PerCP / Cyanine 5.5 | FCM | 562.5 | 100 tests | P11912 | RUO | |
Abbexa | CD79A | abx139331 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (PE) | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | PE | FCM | 400 | 100 tests | P11912 | RUO | |
Abbexa | CD79A | abx139330 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | IHC, FCM | 287.5 | 0.1 mg | P11912 | RUO | |
Abbexa | CD79A | abx139332 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (APC) | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | APC | FCM | 400 | 100 tests | P11912 | RUO | |
Abbexa | CD79A | abx139333 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (FITC) | Human | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | FITC | FCM | 350 | 100 tests | P11912 | RUO | |
Abbexa | CD79A | abx025317 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Mouse | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, WB | 281.25 | 80 µl | P11912 | RUO | |
Abbexa | CD79A | abx025316 | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody | Mouse | Monoclonal | Mouse | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) | Unconjugated | ELISA, WB | 518.75 | 100 µl | P11912 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | CD79A | abx680556 | Human B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Protein | Human | Recombinant | Insect | Unconjugated | SDS-PAGE | 225 | 2 µg | RUO |
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