B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody

Este producto es parte de CD79A molecule
B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody

Pida mas información

935106861

info@markelab.com

Precio

292.5€ (80 µl)

Antibody anti-CD79A

proveedor

Abbexa

reference

abx028431

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.


Background

CD79A, also known as Ig-alpha, is a protein encoded by the CD79A gene in humans. It is a crucial component of the B cell receptor (BCR) complex, playing a significant role in B cell development, activation, and signaling. The BCR complex is essential for the adaptive immune response, allowing B cells to recognize and respond to specific antigens. CD79A, along with CD79B (Ig-beta), forms the signaling component of the BCR, transmitting signals from the antigen-bound surface immunoglobulin (Ig) to the cell's interior, initiating a cascade of intracellular events leading to B cell activation, proliferation, and differentiation.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A)


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB


purification

Purified through a protein A column, followed by peptide affinity purification.


recommended dilution

WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.


buffer

PBS containing 0.09% sodium azide.


size 1

80 µl


size 2

400 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

CD79A


dry ice

No


availability

Shipped within 5-10 working days.


alias

IGA,MB1,MB-1,IGAlpha,Ig-alpha,MB-1 membrane glycoprotein,Membrane-bound immunoglobulin-associated protein,Surface IgM-associated protein,B-cell antigen receptor complex-associated protein alpha chain


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