CD79A antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
CD79A antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab10737
Tested Applications
ELISA, WB, IHC
Description
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex(BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro-and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | CD79a molecule, immunoglobulin-associated alpha (CD79A) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 40 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P11912 |
| Alias | IGA,MB1,MB-1,IGAlpha,Ig-alpha,MB-1 membrane glycoprotein,Membrane-bound immunoglobulin-associated protein,Surface IgM-associated protein,B-cell antigen receptor complex-associated protein alpha chain |
| Background | Antibody anti-CD79A |
| Status | RUO |
| Note | Mol. Weight 40 kDa |
Background
CD79A, also known as Ig-alpha, is a protein encoded by the CD79A gene in humans. It is a crucial component of the B cell receptor (BCR) complex, playing a significant role in B cell development, activation, and signaling. The BCR complex is essential for the adaptive immune response, allowing B cells to recognize and respond to specific antigens. CD79A, along with CD79B (Ig-beta), forms the signaling component of the BCR, transmitting signals from the antigen-bound surface immunoglobulin (Ig) to the cell's interior, initiating a cascade of intracellular events leading to B cell activation, proliferation, and differentiation.
Productos relacionados
B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody
CD79A Antibody is a Rabbit Polyclonal Antibody against CD79A.…
Ver producto
B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody
Rabbit polyclonal antibody against CD79A protein. Immunogen region is Internal.…
Ver producto
CD79 alpha Antibody
CD79 alpha Antibody is a Rabbit Polyclonal antibody against Human and Mouse.…
Ver producto