B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (Biotin)

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Description
B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (Biotin) is a Mouse monoclonal antibody against B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) conjugated to Biotin.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Immunogen: IgM complex isolated from Daudi cells |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | FCM: 1-5 μg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Biotin |
| Isotype | IgG1 Kappa |
| Purification | Purified by size-exclusion chromatography. |
| Size 1 | 0.1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC, FCM, IP |
| Buffer | PBS, pH 7.4, containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P11912 |
| Gene ID | 973 |
| NCBI Accession | NP_001774.1, NP_067612.1 |
| Background | Antibody anti-CD79A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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CD79A antibody
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex(BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro-and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
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CD79A antibody
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex(BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro-and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
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