B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody

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Description
B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody is a Mouse Monoclonal antibody for the detection of B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) in Human samples.
Documents del producto
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A)  | 
| Host | Mouse  | 
| Reactivity | Human  | 
| Clonality | Monoclonal  | 
| Conjugation | Unconjugated  | 
| Isotype | IgG1 Kappa  | 
| Clone ID | J912  | 
| Purity | > 95%  | 
| Purification | Purified by Protein A/G affinity chromatography.  | 
| Size 1 | 50 µg  | 
| Size 2 | 100 µg  | 
| Form | Liquid  | 
| Tested Applications | FCM  | 
| Buffer | 0.01 M PBS, pH 7.4.  | 
| Availability | Shipped within 5-12 working days.  | 
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles.  | 
| Dry Ice | No  | 
| UniProt ID | P11912  | 
| Gene ID | 973  | 
| NCBI Accession | NP_001774.1  | 
| Alias | IGA,MB1,MB-1,IGAlpha,Ig-alpha,MB-1 membrane glycoprotein,Membrane-bound immunoglobulin-associated protein,Surface IgM-associated protein,B-cell antigen receptor complex-associated protein alpha chain  | 
| Background | Antibody anti-CD79A  | 
| Status | RUO  | 
| Note | Concentration: 1 mg/ml -  | 
Descripción
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CD79A antibody
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex(BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro-and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
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CD79A antibody
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex(BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro-and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Ver Producto