B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody

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Description
B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody is a Mouse Monoclonal antibody for the detection of B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) in Human samples.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Isotype | IgG1 Kappa |
Clone ID | J912 |
Purity | > 95% |
Purification | Purified by Protein A/G affinity chromatography. |
Size 1 | 50 µg |
Size 2 | 100 µg |
Form | Liquid |
Tested Applications | FCM |
Buffer | 0.01 M PBS, pH 7.4. |
Availability | Shipped within 5-12 working days. |
Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
Dry Ice | No |
UniProt ID | P11912 |
Gene ID | 973 |
NCBI Accession | NP_001774.1 |
Alias | IGA,MB1,MB-1,IGAlpha,Ig-alpha,MB-1 membrane glycoprotein,Membrane-bound immunoglobulin-associated protein,Surface IgM-associated protein,B-cell antigen receptor complex-associated protein alpha chain |
Background | Antibody anti-CD79A |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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anti- CD79A antibody
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex(BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro-and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
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anti- CD79A antibody
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex(BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro-and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Ver Producto