B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (FITC)
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Description
B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Antibody (FITC) is a FITC-conjugated Mouse monoclonal antibody for the detection of B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat, Dog, Chicken, Rabbit, Guinea pig, Horse, Cow, Pig |
| Recommended Dilution | FCM: 10 µl/100 µl whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Isotype | IgG1 Kappa |
| Clone ID | N921 |
| Purification | Purified by size-exclusion chromatography. |
| Size 1 | 100 tests |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | PBS, pH 7.4, 15 mM sodium azide. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at 2-8°C in the dark. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P11912 |
| Gene ID | 973 |
| Alias | IGA,MB1,MB-1,IGAlpha,Ig-alpha,MB-1 membrane glycoprotein,Membrane-bound immunoglobulin-associated protein,Surface IgM-associated protein,B-cell antigen receptor complex-associated protein alpha chain |
| Background | Antibody anti-CD79A |
| Status | RUO |
Descripción
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anti- CD79A antibody
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex(BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro-and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
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anti- CD79A antibody
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex(BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro-and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
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