Human B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Protein

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Description
Human B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) Protein is a recombinant Human protein produced in a Mammalian cell expression system.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain (CD79A) |
| Host | Mammalian cells |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Arg143 Tag: C-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 16.73 kDa |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, SDS-PAGE |
| Buffer | 0.01 M PBS, pH 7.4. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20 °C to 80°C. Avoid repeated freeze-thaw cycles. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | P11912 |
| Alias | IGA,MB1,MB-1,IGAlpha,Ig-alpha,MB-1 membrane glycoprotein,Membrane-bound immunoglobulin-associated protein,Surface IgM-associated protein,B-cell antigen receptor complex-associated protein alpha chain |
| Background | Protein CD79A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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CD79A antibody
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex(BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro-and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
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CD79A antibody
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex(BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro-and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
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