Family main features
Adhesion G protein-coupled receptor A (ADGRA) is a subgroup of the adhesion G protein-coupled receptor (GPCR) family that plays critical roles in cell-cell and cell-matrix interactions. ADGRA receptors typically consist of a large extracellular domain responsible for ligand binding, a seven-transmembrane domain, and an intracellular domain linked to G protein signaling pathways. These receptors are involved in diverse biological processes, including cell adhesion, migration, angiogenesis, and neuronal development. ADGRA receptors mediate adhesion through interactions with extracellular matrix components, cell adhesion molecules, or other cells. Dysregulation of ADGRA signaling has been implicated in various diseases, including cancer metastasis, cardiovascular disorders, and neurological conditions. Research on ADGRA receptors provides insights into their roles in cellular physiology and pathology, offering potential targets for therapeutic intervention in a wide range of diseases. Ongoing studies continue to elucidate the molecular mechanisms underlying ADGRA receptor function and their implications for human health.
ADGRA receptors share common structural features typical of adhesion GPCRs:
The ADGRA subfamily consists of several receptors, classified based on their structural and functional properties:
These receptors differ in their specific extracellular adhesion domains and tissue distribution but share common signaling mechanisms.
ADGRA receptors are involved in various crucial biological processes:
ADGRA receptors interact with a variety of extracellular and intracellular molecules:
Dysregulation or mutations in ADGRA receptors are associated with several clinical conditions:
ADGRA receptors are a subfamily of adhesion GPCRs that play critical roles in cell adhesion, signaling, and development. These receptors are characterized by their extracellular adhesion domains, 7-transmembrane structure, and intracellular signaling capabilities. They are involved in essential biological processes, including tissue integrity, immune responses, and neural development. Dysregulation of ADGRA receptors is associated with various diseases, including cancer, developmental disorders, and cardiovascular conditions. Understanding the structure, function, and interactions of ADGRA receptors provides valuable insights into their roles in health and disease.
Adhesion G protein-coupled receptor A1(ADGRA1)
ADGRA1,GPR123
Adhesion G protein-coupled receptor A2(ADGRA2)
ADGRA2,GPR124
Adhesion G protein-coupled receptor A3(ADGRA3)
ADGRA3,TEM5L,TEM5-like,PGR21,GPR125
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Primary Antibodies, ELISA Kits) relacionados con ADGRA - Adhesion G protein-coupled receptor A
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 23 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
Contacta con nosotros en info@markelab.com, si necesitas mas informacion o alguna aclaracion. Te garantizamos respuesta en menos de 24 h.
provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | ADGRA2 | EH4394 | Human GPR124 (G Protein Coupled Receptor 124) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.313-20ng/ml | 96T | Q96PE1 | RUO | ||
Abbexa | ADGRA1 | abx387641 | Human Adhesion G Protein Coupled Receptor A1 / GPR123 (ADGRA1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q86SQ6 | RUO |
Abbexa | ADGRA2 | abx525796 | Human G-protein coupled receptor 124 (ADGRA2) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q96PE1 | RUO | ||
Abbexa | ADGRA3 | abx525798 | Human Probable G-protein coupled receptor 125 (ADGRA3) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8IWK6 | RUO | ||
Abbexa | ADGRA2 | abx525797 | Mouse G-protein coupled receptor 124 (ADGRA2) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q91ZV8 | RUO | ||
Abbexa | ADGRA3 | abx525799 | Mouse Probable G-protein coupled receptor 125 (ADGRA3) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q7TT36 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | ADGRA1 | FNab03592 | anti- GPR123-Specific antibody | human | polyclonal | Rabbit | G protein-coupled receptor 123 | IgG | Unconjugated | ELISA, IHC | 100µg | Q86SQ6 | RUO | |
Abbexa | ADGRA1 | abx375096 | Adhesion G Protein Coupled Receptor A1 (GPR123) Antibody | Human | Polyclonal | Rabbit | Adhesion G Protein Coupled Receptor A1 (GPR123) | Unconjugated | ELISA, IF/ICC | 337.5 | 100 µg | Q86SQ6 | RUO | |
Abbexa | ADGRA1 | abx322851 | Adhesion G Protein-Coupled Receptor A1 (ADGRA1) Antibody | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor A1 (ADGRA1) | Unconjugated | ELISA, IF/ICC | 187.5 | 50 µg | Q86SQ6 | RUO | |
Abbexa | ADGRA1 | abx233592 | GPR123-Specific Antibody | Human | Polyclonal | Rabbit | GPR123-Specific | Unconjugated | ELISA, IHC | 350 | 100 µg | Q86SQ6 | RUO | |
Abbexa | ADGRA2 | abx334595 | Adhesion G Protein-Coupled Receptor A2 (ADGRA2) Antibody (Biotin) | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor A2 (ADGRA2) | Biotin | ELISA | 162.5 | 20 µg | Q96PE1 | RUO | |
Abbexa | ADGRA2 | abx334594 | Adhesion G Protein-Coupled Receptor A2 (ADGRA2) Antibody (FITC) | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor A2 (ADGRA2) | FITC | 162.5 | 20 µg | Q96PE1 | RUO | ||
Abbexa | ADGRA2 | abx334593 | Adhesion G Protein-Coupled Receptor A2 (ADGRA2) Antibody (HRP) | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor A2 (ADGRA2) | HRP | ELISA | 162.5 | 20 µg | Q96PE1 | RUO | |
Abbexa | ADGRA2 | abx325673 | Adhesion G Protein-Coupled Receptor A2 (ADGRA2) Antibody | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor A2 (ADGRA2) | Unconjugated | ELISA, WB, IF/ICC | 187.5 | 50 µg | Q96PE1 | RUO | |
Abbexa | ADGRA2 | abx015297 | G-Protein Coupled Receptor 124 (GPR124) Antibody | Human | Polyclonal | Rabbit | G-Protein Coupled Receptor 124 (GPR124) | Unconjugated | ELISA, IF/ICC | 43.75 | 10 µg | Q96PE1 | RUO | |
Abbexa | ADGRA2 | abx212549 | Adhesion G Protein-Coupled Receptor A2 (ADGRA2) Antibody | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor A2 (ADGRA2) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | Q96PE1 | RUO | |
Abbexa | ADGRA2 | abx212987 | Adhesion G Protein-Coupled Receptor A2 (ADGRA2) Antibody | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor A2 (ADGRA2) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q96PE1 | RUO | |
Abbexa | ADGRA2 | abx338824 | Adhesion G Protein-Coupled Receptor A2 (ADGRA2) Antibody | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor A2 (ADGRA2) | Unconjugated | ELISA, WB, IHC, IF/ICC | 162.5 | 20 µg | Q96PE1 | RUO | |
Abbexa | ADGRA3 | abx308486 | Adhesion G Protein-Coupled Receptor A3 (ADGRA3) Antibody | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor A3 (ADGRA3) | Unconjugated | ELISA, IF/ICC | 162.5 | 20 µg | Q8IWK6 | RUO | |
Abbexa | ADGRA3 | abx308489 | Adhesion G Protein-Coupled Receptor A3 (ADGRA3) Antibody (Biotin) | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor A3 (ADGRA3) | Biotin | ELISA | 162.5 | 20 µg | Q8IWK6 | RUO | |
Abbexa | ADGRA3 | abx308487 | Adhesion G Protein-Coupled Receptor A3 (ADGRA3) Antibody (HRP) | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor A3 (ADGRA3) | HRP | ELISA | 162.5 | 20 µg | Q8IWK6 | RUO | |
Abbexa | ADGRA3 | abx432134 | G-Protein Coupled Receptor 125 (GPR125) Antibody | Human | Polyclonal | Goat | G-Protein Coupled Receptor 125 (GPR125) | Unconjugated | P-ELISA, WB, IHC | 387.5 | 200 µl | RUO | ||
Abbexa | ADGRA3 | abx308488 | Adhesion G Protein-Coupled Receptor A3 (ADGRA3) Antibody (FITC) | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor A3 (ADGRA3) | FITC | 162.5 | 20 µg | Q8IWK6 | RUO |
Te recomendamos que si no encuentras lo que buscas, utilices el buscador, refinando la búsqueda según tu criterio y usando Alias, o bien contacta con nosotros.