Human GPR124 (G Protein Coupled Receptor 124) ELISA Kit
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name
Human GPR124 (G Protein Coupled Receptor 124) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH4394
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.313-20ng/ml |
| Size 1 | 96T |
| Sample Type | Serum,Plasma,Tissue homogenates,Other biological fluids |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 6 months |
| UniProt ID | Q96PE1 |
| Alias | ADGRA2,GPR125 |
| Background | Elisa Kits ADGRA2 |
| Status | RUO |
ADGRA2, also known as GPR124, is critical for angiogenesis, particularly in the central nervous system. It interacts with vascular endothelial growth factor (VEGF) signaling, mediating blood-brain barrier formation and vascular integrity. ADGRA2's extracellular domain includes thrombospondin type-1 repeats (TSRs), essential for binding to extracellular matrix components. This receptor also participates in Wnt/β-catenin signaling, pivotal for vascular development and stem cell maintenance. ADGRA2 is predominantly expressed in endothelial cells and neural tissues. Dysregulated expression or mutations in ADGRA2 have been linked to neurovascular disorders, glioblastomas, and other cancers, underscoring its significance in vascular biology.
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