Adhesion G Protein-Coupled Receptor A2 (ADGRA2) Antibody (Biotin)
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Adhesion G Protein-Coupled Receptor A2 (ADGRA2) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx334595
tested applications
ELISA
Description
ADGRA2 Antibody (Biotin) is a Rabbit Polyclonal against ADGRA2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adhesion G Protein-Coupled Receptor A2 (ADGRA2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96PE1 |
| Gene ID | 25960 |
| Alias | ADGRA2,GPR124 |
| Background | Antibody anti-ADGRA2 |
| Status | RUO |
Descripción
ADGRA2, also known as GPR124, is critical for angiogenesis, particularly in the central nervous system. It interacts with vascular endothelial growth factor (VEGF) signaling, mediating blood-brain barrier formation and vascular integrity. ADGRA2's extracellular domain includes thrombospondin type-1 repeats (TSRs), essential for binding to extracellular matrix components. This receptor also participates in Wnt/β-catenin signaling, pivotal for vascular development and stem cell maintenance. ADGRA2 is predominantly expressed in endothelial cells and neural tissues. Dysregulated expression or mutations in ADGRA2 have been linked to neurovascular disorders, glioblastomas, and other cancers, underscoring its significance in vascular biology.
Related Products
Human GPR124 (G Protein Coupled Receptor 124) ELISA Kit
Ver Producto
G-Protein Coupled Receptor 124 (GPR124) Antibody
Rabbit polyclonal antibody against GPR124 protein. Immunogen region is C-terminal.
Ver Producto
Adhesion G Protein-Coupled Receptor A2 (ADGRA2) Antibody
GPR124 Antibody is a Rabbit Polyclonal against GPR124.
Ver Producto