Human Adhesion G Protein Coupled Receptor A1 / GPR123 (ADGRA1) ELISA Kit

Este producto es parte de ADGRA - Adhesion G protein-coupled receptor A
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Adhesion G Protein Coupled Receptor A1 / GPR123 (ADGRA1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx387641
tested applications
ELISA

Description

Human Adhesion G Protein Coupled Receptor A1 / GPR123 (ADGRA1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human GPR123 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Adhesion G Protein Coupled Receptor A1 / GPR123 (ADGRA1)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.094 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-12 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q86SQ6
Gene ID
84435
OMIM
612302
Alias
ADGRA1,GPR123
Background
Elisa kits for ADGRA1
Status
RUO
Note
Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ADGRA1, also known as GPR123, is a member of the adhesion G protein-coupled receptor (GPCR) family, characterized by long extracellular domains facilitating cell-cell or cell-matrix interactions. This protein is highly expressed in the central nervous system and is implicated in neurodevelopmental processes, including axon guidance and synaptic formation. ADGRA1 contains a GPCR autoproteolysis-inducing (GAIN) domain, allowing for self-cleavage to regulate receptor activation. Its precise signaling mechanisms are still being studied, but it is believed to influence intracellular pathways like cAMP production and calcium mobilization. Dysregulation of ADGRA1 has been associated with neurological disorders and certain cancers, highlighting its relevance in both physiology and pathology.

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