Human Adhesion G Protein Coupled Receptor A1 / GPR123 (ADGRA1) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits ADGRA1
proveedor
Abbexareference
abx387641Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Adhesion G Protein Coupled Receptor A1 / GPR123 (ADGRA1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human GPR123 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ADGRA1, also known as GPR123, is a member of the adhesion G protein-coupled receptor (GPCR) family, characterized by long extracellular domains facilitating cell-cell or cell-matrix interactions. This protein is highly expressed in the central nervous system and is implicated in neurodevelopmental processes, including axon guidance and synaptic formation. ADGRA1 contains a GPCR autoproteolysis-inducing (GAIN) domain, allowing for self-cleavage to regulate receptor activation. Its precise signaling mechanisms are still being studied, but it is believed to influence intracellular pathways like cAMP production and calcium mobilization. Dysregulation of ADGRA1 has been associated with neurological disorders and certain cancers, highlighting its relevance in both physiology and pathology.
Características del producto
category
ELISA Kits
immunogen target
Adhesion G Protein Coupled Receptor A1 / GPR123 (ADGRA1)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.094 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
ADGRA1,GPR123
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
ADGRA1
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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