Mouse G-protein coupled receptor 124 (ADGRA2) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits ADGRA2
proveedor
Abbexareference
abx525797Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse G-protein coupled receptor 124 (ADGRA2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse G-protein coupled receptor 124 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ADGRA2, also known as GPR124, is critical for angiogenesis, particularly in the central nervous system. It interacts with vascular endothelial growth factor (VEGF) signaling, mediating blood-brain barrier formation and vascular integrity. ADGRA2's extracellular domain includes thrombospondin type-1 repeats (TSRs), essential for binding to extracellular matrix components. This receptor also participates in Wnt/β-catenin signaling, pivotal for vascular development and stem cell maintenance. ADGRA2 is predominantly expressed in endothelial cells and neural tissues. Dysregulated expression or mutations in ADGRA2 have been linked to neurovascular disorders, glioblastomas, and other cancers, underscoring its significance in vascular biology.
Características del producto
category
ELISA Kits
immunogen target
G-protein coupled receptor 124 (ADGRA2)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
ADGRA2,GPR124
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
ADGRA2
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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