Mouse G-protein coupled receptor 124 (ADGRA2) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse G-protein coupled receptor 124 (ADGRA2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx525797
tested applications
ELISA
Description
Mouse G-protein coupled receptor 124 (ADGRA2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse G-protein coupled receptor 124 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | G-protein coupled receptor 124 (ADGRA2) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q91ZV8 |
| Gene ID | 78560 |
| Alias | ADGRA2,GPR124 |
| Background | Elisa kits for ADGRA2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ADGRA2, also known as GPR124, is critical for angiogenesis, particularly in the central nervous system. It interacts with vascular endothelial growth factor (VEGF) signaling, mediating blood-brain barrier formation and vascular integrity. ADGRA2's extracellular domain includes thrombospondin type-1 repeats (TSRs), essential for binding to extracellular matrix components. This receptor also participates in Wnt/β-catenin signaling, pivotal for vascular development and stem cell maintenance. ADGRA2 is predominantly expressed in endothelial cells and neural tissues. Dysregulated expression or mutations in ADGRA2 have been linked to neurovascular disorders, glioblastomas, and other cancers, underscoring its significance in vascular biology.
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