Family main features
SIRT3, also known as NAD-dependent protein deacetylase sirtuin-3, is a member of the sirtuin family of proteins, which are involved in various cellular processes including metabolism, stress response, and aging. SIRT3 is primarily localized in the mitochondria, the cellular organelles responsible for energy production and other critical metabolic functions. One of the key functions of SIRT3 is its role in regulating mitochondrial metabolism. SIRT3 targets several proteins within the mitochondria, including enzymes involved in oxidative phosphorylation, the citric acid cycle (also known as the Krebs cycle), fatty acid metabolism, and antioxidant defense mechanisms. By deacetylating these target proteins, SIRT3 enhances their activity, leading to increased energy production, improved mitochondrial function, and protection against oxidative stress.SIRT3 has been shown to play a critical role in cellular responses to stress, including oxidative stress and nutrient deprivation. It promotes cell survival under conditions of metabolic stress by regulating mitochondrial metabolism and maintaining cellular energy balance. Additionally, SIRT3 has been implicated in the regulation of apoptosis and the cellular response to DNA damage.
Sirtuin 3 (SIRT3) is a mitochondrial NAD+-dependent deacetylase that plays a crucial role in regulating mitochondrial function, energy metabolism, and cellular stress responses. By deacetylating key metabolic enzymes and antioxidant proteins, SIRT3 enhances mitochondrial efficiency, promotes fatty acid oxidation, and reduces oxidative stress. SIRT3 is involved in various physiological processes, including aging, metabolic adaptation, and apoptosis regulation. Dysregulation of SIRT3 is associated with metabolic disorders, aging, cardiovascular diseases, and cancer, making it a potential therapeutic target for these conditions.
NAD-dependent protein deacetylase sirtuin-3 (SIRT3)
SIR2L3,NAD-dependent protein deacetylase sirtuin-3 mitochondrial,SIR2-like protein 3,SIR2L3,hSIRT3
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits, CLIA Kits) relacionados con SIRT3 - Sirtuin 3
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 45 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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FineTest | SIRT3 | EH4451 | Human SIRT3(NAD-dependent ADP-ribosyltransferase sirtuin-4) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.156-10ng/ml | 96T | O75094 | RUO | ||
Abbexa | SIRT3 | abx153094 | Human Sirtuin 3 (SIRT3) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.061 ng/ml | 618.75 | 96 tests | Q9NTG7 | RUO |
Abbexa | SIRT3 | abx494778 | Human Sirtuin 3 (SIRT3) CLIA Kit | Human | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.112 ng/ml | 812.5 | 96 tests | RUO | |
FineTest | SIRT3 | EM0731 | Mouse Sirt3(NAD-dependent deacetylase sirtuin-3) ELISA Kit | mouse | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.313-20ng/ml | 96T | Q8R104 | RUO | ||
Abbexa | SIRT3 | abx154678 | Mouse Sirtuin 3 (SIRT3) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.06 ng/ml | 618.75 | 96 tests | RUO | |
Abbexa | SIRT3 | abx494779 | Mouse Sirtuin 3 (SIRT3) CLIA Kit | Mouse | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.054 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | SIRT3 | abx156091 | Rat Sirtuin 3 (SIRT3) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.06 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | SIRT3 | abx494780 | Rat Sirtuin 3 (SIRT3) CLIA Kit | Rat | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.053 ng/ml | 812.5 | 96 tests | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
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FineTest | SIRT3 | FNab07881 | anti- SIRT3 antibody | human | polyclonal | Rabbit | sirtuin (silent mating type information regulation 2 homolog) 3 | IgG | Unconjugated | ELISA, WB, IHC, IF | 100µg | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx321567 | Sirtuin 3 (SIRT3) Antibody | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | ELISA, WB, IHC | 237.5 | 50 µl | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx272368 | Sirtuin 3 (SIRT3) Antibody (Biotin) | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Biotin | WB, IHC, IF/ICC | 362.5 | 200 µl | RUO | ||
Abbexa | SIRT3 | abx321451 | Sirtuin 3 (SIRT3) Antibody | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | ELISA, WB, IHC | 237.5 | 50 µl | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx224230 | Sirtuin 3 (SIRT3) Antibody | Human | Monoclonal | Mouse | Sirtuin 3 (SIRT3) | ELISA | 362.5 | 100 µl | Q9NTG7 | RUO | ||
Abbexa | SIRT3 | abx273581 | Sirtuin 3 (SIRT3) Antibody (FITC) | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | FITC | WB, IHC, IF/ICC | 437.5 | 200 µl | RUO | ||
Abbexa | SIRT3 | abx324025 | Sirtuin 3 (SIRT3) Antibody | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | ELISA, WB | 187.5 | 50 µg | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx100645 | Sirtuin 3 (SIRT3) Antibody | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx100647 | Sirtuin 3 (SIRT3) Antibody | Human | Monoclonal | Mouse | Sirtuin 3 (SIRT3) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | RUO | ||
Abbexa | SIRT3 | abx028151 | Sirtuin 3 (SIRT3) Antibody | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | ELISA, WB | 250 | 80 µl | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx316589 | Sirtuin 3 (SIRT3) Antibody (FITC) | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | FITC | 162.5 | 20 µg | Q9NTG7 | RUO | ||
Abbexa | SIRT3 | abx224373 | Sirtuin 3 (SIRT3) Antibody | Human | Monoclonal | Mouse | Sirtuin 3 (SIRT3) | Unconjugated | ELISA, WB, FCM | 362.5 | 100 µl | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx015065 | Sirtuin 3 (SIRT3) Antibody | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | ELISA, WB | 43.75 | 10 µg | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx433275 | Sirtuin 3 (SIRT3) Antibody | Human | Polyclonal | Goat | Sirtuin 3 (SIRT3) | Unconjugated | P-ELISA, WB | 387.5 | 200 µl | RUO | ||
Abbexa | SIRT3 | abx036063 | Sirtuin 3 (SIRT3) Antibody | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | SIRT3 | abx316588 | Sirtuin 3 (SIRT3) Antibody (HRP) | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | HRP | ELISA | 162.5 | 20 µg | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx316590 | Sirtuin 3 (SIRT3) Antibody (Biotin) | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Biotin | ELISA | 162.5 | 20 µg | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx318089 | Sirtuin 3 (SIRT3) Antibody | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | ELISA, WB, IF/ICC | 162.5 | 20 µg | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx211521 | Sirtuin 3 (SIRT3) Antibody | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx213139 | Sirtuin 3 (SIRT3) Antibody | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx032747 | Sirtuin 3 (SIRT3) Antibody | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | ELISA, WB, IHC | 281.25 | 80 µl | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx004372 | Sirtuin 3 (SIRT3) Antibody | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | WB, IHC, IF/ICC | 200 | 20 µl | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx005514 | Sirtuin 3 (SIRT3) Antibody | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | WB, IHC, IF/ICC, IP | 175 | 20 µl | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx237881 | Sirtuin 3 (SIRT3) Antibody | Human | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | ELISA, WB, IHC, IF/ICC | 350 | 100 µg | Q9NTG7 | RUO | |
Abbexa | SIRT3 | abx432056 | Sirtuin 3 (SIRT3) Antibody | Mouse | Polyclonal | Goat | Sirtuin 3 (SIRT3) | Unconjugated | P-ELISA, WB, IF/ICC, FCM | 387.5 | 200 µl | RUO | ||
Abbexa | SIRT3 | abx129703 | Sirtuin 3 (SIRT3) Antibody | Mouse | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | Q8R104 | RUO | |
Abbexa | SIRT3 | abx100648 | Sirtuin 3 (SIRT3) Antibody | Rat | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Unconjugated | WB, IHC, IF/ICC | 287.5 | 100 µl | C6ZII9 | RUO | |
Abbexa | SIRT3 | abx273295 | Sirtuin 3 (SIRT3) Antibody (Biotin) | Rat | Polyclonal | Rabbit | Sirtuin 3 (SIRT3) | Biotin | WB, IHC, IF/ICC | 387.5 | 200 µl | RUO | ||
Abbexa | SIRT3 | abx174558 | Sirtuin 3 (SIRT3) Antibody | Rat | Monoclonal | Mouse | Sirtuin 3 (SIRT3) | Unconjugated | WB, IHC, IF/ICC | 850 | 1 ml | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | SIRT3 | abx651440 | Mouse Sirtuin 3 (SIRT3) Protein (Active) | Mouse | E. coli | Unconjugated | WB, SDS-PAGE | 600 | 50 µg | Q8R104 | RUO | |
Abbexa | SIRT3 | abx651441 | Rat Sirtuin 3 (SIRT3) Protein (Active) | Rat | E. coli | Unconjugated | WB, SDS-PAGE | 637.5 | 50 µg | C6ZII9 | RUO | |
Abbexa | SIRT3 | abx166415 | Human Sirtuin 3 (SIRT3) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 200 | 10 µg | RUO | |
Abbexa | SIRT3 | abx262846 | Sirtuin-3 Protein | Recombinant | Unconjugated | SDS-PAGE | 225 | 2 µg | Q9NTG7 | RUO | ||
Abbexa | SIRT3 | abx069102 | Rat Sirtuin 3 (SIRT3) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | C6ZII9 | RUO |
FineTest | SIRT3 | P6799 | Recombinant Human SIRT3 | Human | Recombinant | E.Coli | Western Blot,ELISA | 50μg | Q9NTG7 | RUO | ||
Abbexa | SIRT3 | abx655827 | Human Sirtuin 3 (SIRT3) Protein (Active) | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 525 | 50 µg | Q9NTG7 | RUO |
Abbexa | SIRT3 | abx167224 | Mouse Sirtuin 3 (SIRT3) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | RUO |
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