NAD-Dependent Protein Deacetylase Sirtuin-3, Mitochondrial (SIRT3) Antibody
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Description
NAD-Dependent Protein Deacetylase Sirtuin-3, Mitochondrial (SIRT3) Antibody is a Rabbit polyclonal antibody for the detection of Human NAD-Dependent Protein Deacetylase Sirtuin-3, Mitochondrial (SIRT3).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: NAD-Dependent Protein Deacetylase Sirtuin-3, Mitochondrial (SIRT3) Immunogen: Recombinant NAD-Dependent Protein Deacetylase Sirtuin-3, Mitochondrial (Lys122-Lys399) expressed in E. coli. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NTG7 |
| Gene ID | 23410 |
| NCBI Accession | NP_001017524.1 |
| Alias | SIR2L3,NAD-dependent protein deacetylase sirtuin-3 mitochondrial,SIR2-like protein 3,SIR2L3,hSIRT3 |
| Background | Antibody anti-SIRT3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.
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