Family main features
Signal-transducing adaptor proteins (STAPs) are integral components of intracellular signaling pathways. They serve as platforms that facilitate the assembly of signaling complexes, thereby propagating and modulating cellular signals in response to external stimuli. These proteins typically contain multiple protein-protein interaction domains, enabling them to interact with various signaling molecules. STAPs play crucial roles in various physiological processes, including immune responses, cell growth, differentiation, and apoptosis. Their dysregulation is often associated with numerous diseases, including cancers, immunodeficiencies, and inflammatory disorders.
STAPs are characterized by several distinct domains:
STAPs can be classified based on their domain architecture and the signaling pathways they are involved in. Some well-known STAP families include:
STAPs perform several critical functions in cellular signaling:
Dysregulation of STAPs is implicated in various diseases:
Signal-transducing adaptor proteins (STAPs) are crucial for the regulation and propagation of cellular signals. They possess domains such as PH, SH2, and proline-rich regions that facilitate interactions with a variety of signaling molecules. By serving as scaffolds, they ensure efficient and specific signal transduction, impacting various cellular processes like growth, differentiation, and immune responses. Dysregulation of STAPs is associated with a range of diseases, including cancer, immunodeficiency, and inflammatory disorders. Understanding the precise mechanisms of STAP function and regulation can provide insights into potential therapeutic targets for these conditions.
Signal-transducing adaptor protein 1 (STAP1)
STAP1,BRDG1, STAP-1, signal transducing adaptor family member 1
Signal-transducing adaptor protein 2 (STAP2)
STAP-2,Breast tumor kinase substrate,BRK substrate,STAP2,BKS
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits) relacionados con STAP - Signal-transducing adaptor protein
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 27 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | STAP1 | abx574927 | Human Stress Induced Phosphoprotein 1 (STIP1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 3.125 ng/ml - 200 ng/ml | 1.88 ng/ml | 587.5 | 96 tests | P31948 | RUO |
Abbexa | STAP1 | abx547613 | Human Signal-transducing adaptor protein 1 (STAP1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q9ULZ2 | RUO | ||
Abbexa | STAP2 | abx547615 | Human Signal-transducing adaptor protein 2 (STAP2) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q9UGK3 | RUO | ||
Abbexa | STAP1 | abx547614 | Mouse Signal-transducing adaptor protein 1 (STAP1) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q9JM90 | RUO | ||
Abbexa | STAP2 | abx547616 | Mouse Signal-transducing adaptor protein 2 (STAP2) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8R0L1 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | STAP1 | FNab08323 | anti- STIP1 antibody | human | polyclonal | Rabbit | stress-induced-phosphoprotein 1 | IgG | Unconjugated | ELISA, WB, IF | 100µg | P31948 | RUO | |
Abbexa | STAP1 | abx312151 | Signal Transducing Adaptor Protein 1 (STAP1) Antibody (HRP) | Human | Polyclonal | Rabbit | Signal Transducing Adaptor Protein 1 (STAP1) | HRP | ELISA | 162.5 | 20 µg | Q9ULZ2 | RUO | |
Abbexa | STAP1 | abx312153 | Signal Transducing Adaptor Protein 1 (STAP1) Antibody (Biotin) | Human | Polyclonal | Rabbit | Signal Transducing Adaptor Protein 1 (STAP1) | Biotin | ELISA | 162.5 | 20 µg | Q9ULZ2 | RUO | |
Abbexa | STAP1 | abx145700 | Signal Transducing Adaptor Protein 1 (STAP1) Antibody | Human | Polyclonal | Rabbit | Signal Transducing Adaptor Protein 1 (STAP1) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | STAP1 | abx312150 | Signal Transducing Adaptor Protein 1 (STAP1) Antibody | Human | Polyclonal | Rabbit | Signal Transducing Adaptor Protein 1 (STAP1) | Unconjugated | ELISA | 162.5 | 20 µg | Q9ULZ2 | RUO | |
Abbexa | STAP1 | abx312152 | Signal Transducing Adaptor Protein 1 (STAP1) Antibody (FITC) | Human | Polyclonal | Rabbit | Signal Transducing Adaptor Protein 1 (STAP1) | FITC | 162.5 | 20 µg | Q9ULZ2 | RUO | ||
Abbexa | STAP1 | abx031726 | Stress-Induced-Phosphoprotein 1 (STIP1) Antibody | Human | Polyclonal | Rabbit | Stress-Induced-Phosphoprotein 1 (STIP1) | Unconjugated | ELISA, WB, IHC, FCM | 281.25 | 80 µl | P31948 | RUO | |
Abbexa | STAP1 | abx031725 | Stress-Induced-Phosphoprotein 1 (STIP1) Antibody | Human | Polyclonal | Rabbit | Stress-Induced-Phosphoprotein 1 (STIP1) | Unconjugated | ELISA, WB, FCM | 281.25 | 80 µl | P31948 | RUO | |
Abbexa | STAP1 | abx001131 | Stress-Induced-Phosphoprotein 1 (STIP1) Antibody | Human | Polyclonal | Rabbit | Stress-Induced-Phosphoprotein 1 (STIP1) | Unconjugated | WB, IHC | 175 | 20 µl | P31948 | RUO | |
Abbexa | STAP2 | abx430608 | Signal-Transducing Adaptor Protein 2 (STAP2) Antibody | Human | Polyclonal | Goat | Signal-Transducing Adaptor Protein 2 (STAP2) | Unconjugated | P-ELISA, WB, IHC | 387.5 | 200 µl | RUO | ||
Abbexa | STAP2 | abx430607 | Signal-Transducing Adaptor Protein 2 (STAP2) Antibody | Human | Polyclonal | Goat | Signal-Transducing Adaptor Protein 2 (STAP2) | Unconjugated | P-ELISA, WB | 387.5 | 200 µl | RUO | ||
Abbexa | STAP2 | abx026986 | Signal-Transducing Adaptor Protein 2 (STAP2) Antibody | Human | Polyclonal | Rabbit | Signal-Transducing Adaptor Protein 2 (STAP2) | Unconjugated | ELISA, WB, IHC | 281.25 | 80 µl | Q9UGK3 | RUO | |
Abbexa | STAP2 | abx375879 | Signal-Transducing Adaptor Protein 2 (STAP2) Antibody | Human | Polyclonal | Rabbit | Signal-Transducing Adaptor Protein 2 (STAP2) | Unconjugated | ELISA, WB | 337.5 | 100 µg | Q9UGK3 | RUO | |
Abbexa | STAP1 | abx103946 | Signal Transducing Adaptor Protein 1 (STAP1) Antibody | Mouse | Polyclonal | Rabbit | Signal Transducing Adaptor Protein 1 (STAP1) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | RUO | ||
Abbexa | STAP2 | abx431026 | Signal-Transducing Adaptor Protein 2 (Stap2) Antibody | Mouse | Polyclonal | Goat | Signal-Transducing Adaptor Protein 2 (Stap2) | Unconjugated | P-ELISA, WB | 387.5 | 200 µl | RUO | ||
Abbexa | STAP1 | abx130059 | Signal Transducing Adaptor Protein 1 (STAP1) Antibody | Rat | Polyclonal | Rabbit | Signal Transducing Adaptor Protein 1 (STAP1) | Unconjugated | WB, IHC, IF/ICC | 287.5 | 100 µl | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | STAP1 | P5086 | Recombinant Human STIP1 | Human | Recombinant | E.Coli | Western Blot,ELISA | 50μg | P31948 | RUO | ||
Abbexa | STAP1 | abx166139 | Rat Signal Transducing Adaptor Protein 1 (STAP1) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 237.5 | 10 µg | RUO | |
FineTest | STAP1 | P6980 | Recombinant Human STAP-1 | Human | Recombinant | E.Coli | Western Blot,ELISA | 50μg | Q9ULZ2 | RUO | ||
Abbexa | STAP1 | abx069092 | Mouse Signal Transducing Adaptor Protein 1 (STAP1) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | Q9JM90 | RUO |
FineTest | STAP1 | P5982 | Recombinant Mouse STIP1 | Mouse | Recombinant | E.Coli | Western Blot,ELISA | 50μg | Q60864 | RUO | ||
Abbexa | STAP1 | abx260893 | Signal Transducing Adaptor Family Member 1 Protein | Recombinant | Unconjugated | SDS-PAGE | 225 | 5 µg | Q9ULZ2 | RUO |
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