Human Signal-transducing adaptor protein 1 (STAP1) ELISA Kit

Este producto es parte de STAP - Signal-transducing adaptor protein
Human Signal-transducing adaptor protein 1 (STAP1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for STAP1

proveedor

Abbexa

reference

abx547613

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Signal-transducing adaptor protein 1 (STAP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Signal-transducing adaptor protein 1 (STAP1) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

STAP1 is an SH2 domain-containing adaptor protein that regulates cytokine receptor and tyrosine kinase signaling pathways. It interacts with proteins like c-Kit and Jak kinases to mediate downstream activation of signaling cascades such as MAPK, PI3K/Akt, and STAT pathways, influencing cellular proliferation, survival, and differentiation. STAP1 is expressed in hematopoietic and immune cells, where it modulates cytokine responses, immune cell activation, and differentiation. Dysregulation of STAP1 has been linked to immune dysfunction, leukemia, and certain inflammatory disorders due to its role in promoting cytokine-mediated signaling and hematopoietic regulation. Knockdown studies demonstrate impaired cytokine signaling, reduced proliferation, and abnormal immune responses, highlighting its role in fine-tuning signaling pathways during immune regulation and hematopoiesis.

Características del producto

category

ELISA Kits


immunogen target

Signal-transducing adaptor protein 1 (STAP1)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

STAP1,BRDG1, STAP-1, signal transducing adaptor family member 1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

STAP1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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