Human Signal-transducing adaptor protein 1 (STAP1) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for STAP1
proveedor
Abbexareference
abx547613Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Signal-transducing adaptor protein 1 (STAP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Signal-transducing adaptor protein 1 (STAP1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
STAP1 is an SH2 domain-containing adaptor protein that regulates cytokine receptor and tyrosine kinase signaling pathways. It interacts with proteins like c-Kit and Jak kinases to mediate downstream activation of signaling cascades such as MAPK, PI3K/Akt, and STAT pathways, influencing cellular proliferation, survival, and differentiation. STAP1 is expressed in hematopoietic and immune cells, where it modulates cytokine responses, immune cell activation, and differentiation. Dysregulation of STAP1 has been linked to immune dysfunction, leukemia, and certain inflammatory disorders due to its role in promoting cytokine-mediated signaling and hematopoietic regulation. Knockdown studies demonstrate impaired cytokine signaling, reduced proliferation, and abnormal immune responses, highlighting its role in fine-tuning signaling pathways during immune regulation and hematopoiesis.
Características del producto
category
ELISA Kits
immunogen target
Signal-transducing adaptor protein 1 (STAP1)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
STAP1,BRDG1, STAP-1, signal transducing adaptor family member 1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
STAP1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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proveedor
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