STIP1 Antibody is a Rabbit Polyclonal antibody against STIP1. STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]). [supplied by OMIM, Jul 2009]
Primary Antibodies
Polyclonal
Human, Mouse, Rat
Stress-Induced-Phosphoprotein 1 (STIP1)
Rabbit
Unconjugated
Liquid
WB, IHC
Purified by affinity chromatography.
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
20 µl
50 µl
100 µl
200 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
STAP1
No
Shipped within 5-10 working days.
STAP1,BRDG1, STAP-1, signal transducing adaptor family member 1
NP_006810.1
This product is for research use only.
Mediates the association of the molecular chaperones HSC70 and HSP90(HSPCA and HSPCB).
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