Family main features
Prostaglandin E synthase (PTGES) is an enzyme that plays a crucial role in the biosynthesis of prostaglandin E2 (PGE2), a lipid compound that mediates various physiological processes including inflammation, fever, and pain. PTGES catalyzes the isomerization of prostaglandin H2 (PGH2) to PGE2, acting downstream of cyclooxygenases (COX-1 and COX-2) in the prostaglandin biosynthetic pathway. PTGES is particularly associated with the inducible form of cyclooxygenase, COX-2, which is upregulated during inflammatory responses. The enzyme is encoded by the PTGES gene, which is located on chromosome 9 in humans.
PTGES is a membrane-associated protein and is classified as a member of the glutathione-dependent prostaglandin E synthases. The protein structure includes several key domains:
PTGES belongs to a family of enzymes involved in prostaglandin biosynthesis. There are three main types of prostaglandin E synthase:
PTGES has several critical functions:
Prostaglandin E synthase (PTGES) is a key enzyme in the prostaglandin biosynthesis pathway, converting PGH2 to PGE2. It is a membrane-associated protein with critical roles in inflammation, pain, fever, and various physiological processes. PTGES is associated with the inducible COX-2 pathway and is upregulated during inflammatory responses. It has significant implications in inflammatory diseases, cancer, and pain management, making it a potential target for therapeutic interventions. Understanding the structure, function, and regulation of PTGES is essential for developing new treatments for conditions associated with excessive PGE2 production.
Prostaglandin E synthase (PTGES)
MGST1L1,MPGES1,PGES,PIG12,Microsomal prostaglandin E synthase 1,p53-induced gene 12 protein,PP1294,MGST-IV,MGST1L1,TP53I12;,mPGES-1,MGST1-L1
Prostaglandin E Synthase 2 (PTGES2)
C9orf15,GBF-1,GBF1,PGES2,mPGES-2,Membrane-associated prostaglandin E synthase-2
Prostaglandin E synthase 3 (PTGES3)
P23,TEBP,cPGES,Progesterone receptor complex p23,Telomerase-binding protein p23
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, ELISA Kits, Primary Antibodies, CLIA Kits) relacionados con PTGES - Prostaglandin E synthase
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | PTGES | EB0122 | Bovine PTGES(Prostaglandin E synthase) ELISA Kit | bovine | Busacar en las instrucciones | Sandwich ELISA, Double Antibody | 0.313-20ng/ml | 96T | Q95L14 | RUO | ||
Abbexa | PTGES3 | abx514757 | Chicken Prostaglandin E synthase 3 (PTGES3) ELISA Kit | Chicken | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q90955 | RUO | ||
Abbexa | PTGES | abx259201 | Cow Prostaglandin E synthase (PTGES) ELISA Kit | Cow | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich | 0.313 ng/ml - 20 ng/ml | < 0.19 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | PTGES2 | abx555822 | Cow Prostaglandin E Synthase 2 (PTGES2) ELISA Kit | Cow | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q66LN0 | RUO | ||
Abbexa | PTGES3 | abx514756 | Cow Prostaglandin E synthase 3 (PTGES3) ELISA Kit | Cow | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q3ZBF7 | RUO | ||
Abbexa | PTGES | abx517544 | Dog Prostaglandin E synthase (PTGES) ELISA Kit | Dog | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | A0SYQ0 | RUO | ||
FineTest | PTGES | EH1740 | Human PTGES(Prostaglandin E synthase) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 1.563-100ng/ml | 96T | O14684 | RUO | ||
FineTest | PTGES3 | EH1156 | Human PTGES3(Prostaglandin E synthase 3) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.156-10ng/ml | 96T | Q15185 | RUO | ||
Abbexa | PTGES | abx152883 | Human Prostaglandin E Synthase, Microsomal (PTGES) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 1.56 ng/ml - 100 ng/ml | < 0.56 ng/ml | 618.75 | 96 tests | RUO | |
Abbexa | PTGES | abx195998 | Human Prostaglandin E Synthase, Microsomal (PTGES) CLIA Kit | Human | Serum, plasma and other biological fluids. | 31.2 pg/ml - 2000 pg/ml | 18.8 pg/ml | 618.75 | 96 tests | RUO | ||
Abbexa | PTGES | abx251044 | Human Prostaglandin E Synthase, Microsomal (PTGES) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 1.56 ng/ml - 100 ng/ml | 0.94 ng/ml | 562.5 | 96 tests | O14684 | RUO |
Abbexa | PTGES | abx491174 | Human Prostaglandin E Synthase, Microsomal (PTGES) CLIA Kit | Human | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 1.56 ng/ml - 100 ng/ml | < 0.56 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | PTGES2 | abx351904 | Human Prostaglandin E Synthase 2 (PTGES2) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 3.125 ng/ml - 200 ng/ml | 1.88 ng/ml | 525 | 96 tests | Q9H7Z7 | RUO |
Abbexa | PTGES3 | abx250407 | Human Prostaglandin E synthase 3 (PTGES3) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.1 ng/ml | 687.5 | 96 tests | Q15185 | RUO |
Abbexa | PTGES | abx254373 | Mouse Prostaglandin E Synthase, Microsomal (PTGES) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | 0.1 ng/ml | 525 | 96 tests | Q9JM51 | RUO |
Abbexa | PTGES | abx195999 | Mouse Prostaglandin E Synthase, Microsomal (PTGES) CLIA Kit | Mouse | Serum, plasma and other biological fluids. | 31.2 ng/ml - 2000 ng/ml | 18.8 ng/ml | 618.75 | 96 tests | RUO | ||
Abbexa | PTGES | abx517546 | Mouse Prostaglandin E synthase (PTGES) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 31.2 pg/ml - 2000 pg/ml | < 10 pg/ml | 687.5 | 96 tests | Q9JM51 | RUO |
Abbexa | PTGES2 | abx352981 | Mouse Prostaglandin E Synthase 2 (PTGES2) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | 0.1 ng/ml | 556.25 | 96 tests | Q8BWM0 | RUO |
Abbexa | PTGES3 | abx514759 | Mouse Prostaglandin E synthase 3 (PTGES3) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q9R0Q7 | RUO | |
Abbexa | PTGES | abx491175 | Rat Prostaglandin E Synthase, Microsomal (PTGES) CLIA Kit | Rat | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.115 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | PTGES | abx156023 | Rat Prostaglandin E Synthase, Microsomal (PTGES) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.12 ng/ml | 675 | 96 tests | RUO | |
Abbexa | PTGES | abx255962 | Rat Prostaglandin E Synthase, Microsomal (PTGES) ELISA Kit | Rat | Serum,Plasma,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | 0.1 ng/ml | 531.25 | 96 tests | Q9JHF3 | RUO |
Abbexa | PTGES | abx196000 | Rat Prostaglandin E Synthase, Microsomal (PTGES) CLIA Kit | Rat | Serum, plasma and other biological fluids. | 31.2 pg/ml - 2000 pg/ml | 18.8 pg/ml | 618.75 | 96 tests | RUO | ||
Abbexa | PTGES2 | abx353861 | Rat Prostaglandin E Synthase 2 (PTGES2) ELISA Kit | Rat | Serum,Plasma,Other biological fluids | Sandwich | 1.56 ng/ml - 100 ng/ml | 0.94 ng/ml | 525 | 96 tests | D4AE56 | RUO |
Abbexa | PTGES3 | abx514760 | Rat Prostaglandin E synthase 3 (PTGES3) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P83868 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | PTGES2 | FNab06917 | anti- PTGES2 antibody | human | polyclonal | Rabbit | prostaglandin E synthase 2 | IgG | Unconjugated | ELISA, WB, IHC, IF | 100µg | Q9H7Z7 | RUO | |
FineTest | PTGES3 | FNab06918 | anti- PTGES3 antibody | human | polyclonal | Rabbit | prostaglandin E synthase 3(cytosolic) | IgG | Unconjugated | ELISA, IF, IP, WB, FC | 100µg | Q15185 | RUO | |
Abbexa | PTGES | abx174210 | Prostaglandin E Synthase, Microsomal (PTGES) Antibody | Human | Monoclonal | Mouse | Prostaglandin E Synthase, Microsomal (PTGES) | Unconjugated | WB, IHC, IF/ICC | 712.5 | 1 ml | RUO | ||
Abbexa | PTGES | abx103939 | Prostaglandin E Synthase, Microsomal (PTGES) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase, Microsomal (PTGES) | Unconjugated | WB, IHC, IF/ICC | 250 | 100 µl | O14684 | RUO | |
Abbexa | PTGES | abx327267 | Prostaglandin E Synthase, Microsomal (PTGES) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase, Microsomal (PTGES) | Unconjugated | ELISA, WB | 187.5 | 50 µg | O14684 | RUO | |
Abbexa | PTGES2 | abx321836 | Prostaglandin E Synthase 2 (PTGES2) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase 2 (PTGES2) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | Q9H7Z7 | RUO | |
Abbexa | PTGES2 | abx270266 | Prostaglandin E Synthase 2 (PTGES2) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase 2 (PTGES2) | Unconjugated | FCM | 275 | 50 tests | RUO | ||
Abbexa | PTGES2 | abx128925 | Prostaglandin E Synthase 2 (PTGES2) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase 2 (PTGES2) | Unconjugated | WB, IHC, IF/ICC | 250 | 100 µl | RUO | ||
Abbexa | PTGES2 | abx433200 | Prostaglandin E Synthase 2 (PTGES2) Antibody | Human | Polyclonal | Goat | Prostaglandin E Synthase 2 (PTGES2) | Unconjugated | P-ELISA, WB, IHC | 387.5 | 200 µl | RUO | ||
Abbexa | PTGES2 | abx213483 | Prostaglandin E Synthase 2 (PTGES2) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase 2 (PTGES2) | Unconjugated | ELISA, WB | 250 | 50 µl | Q9H7Z7 | RUO | |
Abbexa | PTGES2 | abx213484 | Prostaglandin E Synthase 2 (PTGES2) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase 2 (PTGES2) | Unconjugated | ELISA, WB | 250 | 50 µl | Q9H7Z7 | RUO | |
Abbexa | PTGES2 | abx114731 | Prostaglandin E Synthase 2 (PTGES2) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase 2 (PTGES2) | Unconjugated | ELISA, WB, IHC | 612.5 | 100 µl | Q9H7Z7 | RUO | |
Abbexa | PTGES2 | abx005388 | Prostaglandin E Synthase 2 (PTGES2) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase 2 (PTGES2) | Unconjugated | WB, IHC, IF/ICC | 175 | 20 µl | Q9H7Z7 | RUO | |
Abbexa | PTGES2 | abx236917 | Prostaglandin E Synthase 2 (PTGES2) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase 2 (PTGES2) | Unconjugated | ELISA, WB, IHC, IF/ICC | 350 | 100 µg | Q9H7Z7 | RUO | |
Abbexa | PTGES3 | abx321717 | Prostaglandin E Synthase 3 (PTGES3) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase 3 (PTGES3) | Unconjugated | ELISA | 237.5 | 50 µl | Q15185 | RUO | |
Abbexa | PTGES3 | abx328274 | Prostaglandin E Synthase 3 (PTGES3) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase 3 (PTGES3) | Unconjugated | ELISA, WB, IHC | 187.5 | 50 µg | Q15185 | RUO | |
Abbexa | PTGES3 | abx114732 | Prostaglandin E Synthase 3 (PTGES3) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase 3 (PTGES3) | Unconjugated | ELISA, WB, IF/ICC | 612.5 | 100 µl | Q15185 | RUO | |
Abbexa | PTGES3 | abx241600 | Prostaglandin E synthase 3 (PTGES3) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E synthase 3 (PTGES3) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q15185 | RUO | |
Abbexa | PTGES3 | abx028276 | Prostaglandin E Synthase 3 (PTGES3) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase 3 (PTGES3) | Unconjugated | ELISA, WB | 281.25 | 80 µl | Q15185 | RUO | |
Abbexa | PTGES3 | abx241264 | Prostaglandin E synthase 3 (PTGES3) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E synthase 3 (PTGES3) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q15185 | RUO | |
Abbexa | PTGES3 | abx004071 | Prostaglandin E Synthase 3 (PTGES3) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase 3 (PTGES3) | Unconjugated | WB | 175 | 20 µl | Q15185 | RUO | |
Abbexa | PTGES3 | abx328275 | Prostaglandin E synthase 3 Phospho-Ser113 (PTGES3 pS113) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E synthase 3 Phospho-Ser113 (PTGES3 pS113) | Unconjugated | ELISA, WB, IHC | 187.5 | 50 µg | Q15185 | RUO | |
Abbexa | PTGES3 | abx236918 | Prostaglandin E Synthase 3 (PTGES3) Antibody | Human | Polyclonal | Rabbit | Prostaglandin E Synthase 3 (PTGES3) | Unconjugated | ELISA, WB, IF/ICC, FCM, IP | 350 | 100 µg | Q15185 | RUO | |
Abbexa | PTGES2 | abx102928 | Prostaglandin E Synthase 2 (PTGES2) Antibody | Mouse | Polyclonal | Rabbit | Prostaglandin E Synthase 2 (PTGES2) | Unconjugated | WB, IHC, IF/ICC | 262.5 | 100 µl | RUO | ||
Abbexa | PTGES | abx174211 | Prostaglandin E Synthase, Microsomal (PTGES) Antibody | Rat | Monoclonal | Mouse | Prostaglandin E Synthase, Microsomal (PTGES) | Unconjugated | WB, IHC, IF/ICC | 775 | 1 ml | RUO | ||
Abbexa | PTGES | abx178123 | Prostaglandin E Synthase, Microsomal (PTGES) Antibody | Rat | Polyclonal | Rabbit | Prostaglandin E Synthase, Microsomal (PTGES) | Unconjugated | WB, IHC, IF/ICC | 725 | 1 ml | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | PTGES | abx068702 | Human Prostaglandin E Synthase, Microsomal (PTGES) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | O14684 | RUO |
Abbexa | PTGES | abx654821 | Rat Prostaglandin E Synthase, Microsomal (PTGES) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 200 | 10 µg | RUO | |
Abbexa | PTGES2 | abx166666 | Human Prostaglandin E Synthase 2 (PTGES2) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | Q9H7Z7 | RUO |
Abbexa | PTGES2 | abx073221 | Human Prostaglandin E Synthase 2 (PTGES2) Protein | Human | Recombinant | E. coli | SDS-PAGE | 225 | 5 µg | Q9H7Z7 | RUO | |
FineTest | PTGES2 | P4013 | Recombinant Human PTGES2 | Human | Recombinant | E.Coli | Western Blot,ELISA | 50μg | A6NHH0 | RUO | ||
Abbexa | PTGES2 | abx068701 | Mouse Prostaglandin E Synthase 2 (PTGES2) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | Q8BWM0 | RUO |
FineTest | PTGES2 | P2956 | Recombinant Human PTGES2 | Human | Recombinant | E.Coli | Western Blot, ELISA | 50μg | Q9H7Z7 | RUO | ||
Abbexa | PTGES3 | abx073563 | Human Prostaglandin E Synthase 3 (PTGES3) Protein | Human | Recombinant | E. coli | SDS-PAGE | 225 | 5 µg | Q15185 | RUO |
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