Human Prostaglandin E Synthase 2 (PTGES2) Protein
234€ (5 µg)
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Name
Human Prostaglandin E Synthase 2 (PTGES2) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx073221
Tested Applications
SDS-PAGE
Description
Prostaglandin E Synthase 2 is a recombinant enzyme.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Prostaglandin E Synthase 2 (PTGES2) |
| Host | E. coli |
| Assay Type | Activity: Not tested |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Human |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at 4°C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H7Z7 |
| Alias | C9orf15,GBF-1,GBF1,PGES2,mPGES-2,Membrane-associated prostaglandin E synthase-2 |
| Background | Protein PTGES2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Prostaglandin E Synthase 2 (PTGES2) is an enzyme involved in prostaglandin biosynthesis specifically converting prostaglandin H2 (PGH2) to prostaglandin E2 (PGE2) which is a critical lipid mediator in inflammation fever and pain responses PTGES2 is localized in the cytoplasm and functionally distinct from its microsomal counterpart (mPGES-1) It is constitutively expressed in various tissues and its activity is regulated by cellular stimuli such as cytokines or stress signals PTGES2-derived PGE2 plays a role in modulating immune responses and tissue homeostasis Dysregulation of PTGES2 expression has been implicated in chronic inflammatory diseases such as arthritis and inflammatory bowel disease as well as cancer progression due to PGE2’s role in tumorigenesis and immune evasion PTGES2 is also linked to reproductive functions and fever response through its regulation of the hypothalamic-pituitary-adrenal axis
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