Prostaglandin E Synthase 3 (PTGES3) Antibody
260€ (50 µg)
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935106861
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name
Prostaglandin E Synthase 3 (PTGES3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx456136
tested applications
ELISA, WB, IHC
Description
Prostaglandin E Synthase 3 (PTGES3) Antibody is a Rabbit polyclonal antibody for the detection of Human Prostaglandin E Synthase 3 (PTGES3).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Prostaglandin E Synthase 3 (PTGES3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q15185 |
| Gene ID | 10728 |
| NCBI Accession | NP_001269530.1 |
| Alias | P23,TEBP,cPGES,Progesterone receptor complex p23,Telomerase-binding protein p23 |
| Background | Antibody anti-PTGES3 |
| Status | RUO |
Descripción
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PTGES3 antibody
Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2(PGH2) to prostaglandin E2(PGE2)(PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes(PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway(PubMed:24711448).
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