Mouse Prostaglandin E Synthase 2 (PTGES2) Protein

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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein PTGES2
proveedor
Abbexareference
abx068701Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Prostaglandin E Synthase 2 (PTGES2) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
Prostaglandin E Synthase 2 (PTGES2) is an enzyme involved in prostaglandin biosynthesis specifically converting prostaglandin H2 (PGH2) to prostaglandin E2 (PGE2) which is a critical lipid mediator in inflammation fever and pain responses PTGES2 is localized in the cytoplasm and functionally distinct from its microsomal counterpart (mPGES-1) It is constitutively expressed in various tissues and its activity is regulated by cellular stimuli such as cytokines or stress signals PTGES2-derived PGE2 plays a role in modulating immune responses and tissue homeostasis Dysregulation of PTGES2 expression has been implicated in chronic inflammatory diseases such as arthritis and inflammatory bowel disease as well as cancer progression due to PGE2’s role in tumorigenesis and immune evasion PTGES2 is also linked to reproductive functions and fever response through its regulation of the hypothalamic-pituitary-adrenal axis
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Prostaglandin E Synthase 2 (PTGES2)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 31.3 kDa Observed MW (SDS-PAGE): 30 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Tyr144-Asp384 Tag: N-terminal His tag
expression
Recombinant
purity
> 97%
buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
PTGES2
dry ice
No
availability
Shipped within 5-7 working days.
alias
C9orf15,GBF-1,GBF1,PGES2,mPGES-2,Membrane-associated prostaglandin E synthase-2
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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proveedor
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