Mouse Prostaglandin E Synthase 2 (PTGES2) Protein

Este producto es parte de PTGES - Prostaglandin E synthase
Product Graph
234€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Mouse Prostaglandin E Synthase 2 (PTGES2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx068701
tested applications
WB, SDS-PAGE

Description

Mouse Prostaglandin E Synthase 2 (PTGES2) is a recombinant Mouse protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Prostaglandin E Synthase 2 (PTGES2)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: Tyr144-Asp384
Tag: N-terminal His tag
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Calculated MW: 31.3 kDa  Observed MW (SDS-PAGE): 30 kDa
Expression
Recombinant
Purity
> 97%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
UniProt ID
Q8BWM0
Alias
C9orf15,GBF-1,GBF1,PGES2,mPGES-2,Membrane-associated prostaglandin E synthase-2
Background
Protein PTGES2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 200 µg/ml

Descripción

Prostaglandin E Synthase 2 (PTGES2) is an enzyme involved in prostaglandin biosynthesis specifically converting prostaglandin H2 (PGH2) to prostaglandin E2 (PGE2) which is a critical lipid mediator in inflammation fever and pain responses PTGES2 is localized in the cytoplasm and functionally distinct from its microsomal counterpart (mPGES-1) It is constitutively expressed in various tissues and its activity is regulated by cellular stimuli such as cytokines or stress signals PTGES2-derived PGE2 plays a role in modulating immune responses and tissue homeostasis Dysregulation of PTGES2 expression has been implicated in chronic inflammatory diseases such as arthritis and inflammatory bowel disease as well as cancer progression due to PGE2’s role in tumorigenesis and immune evasion PTGES2 is also linked to reproductive functions and fever response through its regulation of the hypothalamic-pituitary-adrenal axis

Related Products

FNab06917

PTGES2 antibody

The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene.

Ver Producto
P2956

Recombinant Human PTGES2

Ver Producto
P4013

Recombinant Human PTGES2

Ver Producto