Family main features
AADAT, also known as KAT2 (Kynurenine Aminotransferase 2), is an enzyme encoded by the AADAT gene. It belongs to the aminotransferase family of enzymes, which play essential roles in amino acid metabolism. AADAT is primarily expressed in the liver, kidney, and brain. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid
AADAT is a pyridoxal 5'-phosphate (PLP)-dependent enzyme, meaning it requires the cofactor PLP (derived from vitamin B6) for its catalytic activity. Structurally, AADAT consists of a catalytic domain that binds both the PLP cofactor and the substrate, allowing it to carry out the aminotransferase reaction.
AADAT is classified as an aminotransferase enzyme, specifically belonging to the kynurenine aminotransferase (KAT) subfamily. There are multiple subtypes of KAT enzymes in humans, with AADAT being one of them. Other subtypes include KAT1 (AADAT), KAT2, and KAT3, each with distinct tissue distributions and substrate specificities.
Aminoadipate Aminotransferase (AADAT)
KAT2, KATII, KYAT2, KYNURENINE AMINOTRANSFERASE II
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits, CLIA Kits) relacionados con AADAT - Aminoadipate Aminotransferase
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Esta página contiene 21 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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FineTest | AADAT | EH1430 | Human AADAT(Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.313-20ng/ml | 96T | Q8N5Z0 | RUO | ||
Abbexa | AADAT | abx150492 | Human Aminoadipate Aminotransferase (AADAT) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.06 ng/ml | 618.75 | 96 tests | RUO | |
Abbexa | AADAT | abx494414 | Human Aminoadipate Aminotransferase (AADAT) CLIA Kit | Human | Tissue homogenates and other biological fluids. | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.067 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | AADAT | abx516042 | Mouse Aminoadipate Aminotransferase (AADAT) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.079 ng/ml | 687.5 | 96 tests | Q9WVM8 | RUO |
FineTest | AADAT | ER0481 | Rat Aadat(Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial) ELISA Kit | rat | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.156-10ng/ml | 96T | Q64602 | RUO | ||
Abbexa | AADAT | abx256458 | Rat Aminoadipate Aminotransferase (AADAT) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q64602 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | AADAT | FNab00018 | anti- AADAT antibody | human | polyclonal | Rabbit | aminoadipate aminotransferase | IgG | Unconjugated | ELISA, IHC, WB | 100µg | Q8N5Z0 | RUO | |
Abbexa | AADAT | abx432251 | Aminoadipate Aminotransferase (AADAT) Antibody | Human | Polyclonal | Goat | Aminoadipate Aminotransferase (AADAT) | Unconjugated | P-ELISA, WB | 387.5 | 200 µl | RUO | ||
Abbexa | AADAT | abx432252 | Aminoadipate Aminotransferase (AADAT) Antibody | Human | Polyclonal | Goat | Aminoadipate Aminotransferase (AADAT) | Unconjugated | P-ELISA, IHC | 387.5 | 200 µl | RUO | ||
Abbexa | AADAT | abx309666 | Aminoadipate Aminotransferase (AADAT) Antibody (Biotin) | Human | Polyclonal | Rabbit | Aminoadipate Aminotransferase (AADAT) | Biotin | ELISA | 162.5 | 20 µg | Q8N5Z0 | RUO | |
Abbexa | AADAT | abx122386 | Aminoadipate Aminotransferase (AADAT) Antibody | Human | Polyclonal | Rabbit | Aminoadipate Aminotransferase (AADAT) | Unconjugated | ELISA, WB | 337.5 | 100 µg | RUO | ||
Abbexa | AADAT | abx131229 | Aminoadipate Aminotransferase (AADAT) Antibody | Human | Polyclonal | Rabbit | Aminoadipate Aminotransferase (AADAT) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | Q8N5Z0 | RUO | |
Abbexa | AADAT | abx171194 | Aminoadipate Aminotransferase (AADAT) Antibody | Human | Monoclonal | Mouse | Aminoadipate Aminotransferase (AADAT) | Unconjugated | WB, IHC, IF/ICC | 787.5 | 1 ml | RUO | ||
Abbexa | AADAT | abx309664 | Aminoadipate Aminotransferase (AADAT) Antibody (HRP) | Human | Polyclonal | Rabbit | Aminoadipate Aminotransferase (AADAT) | HRP | ELISA | 162.5 | 20 µg | Q8N5Z0 | RUO | |
Abbexa | AADAT | abx309665 | Aminoadipate Aminotransferase (AADAT) Antibody (FITC) | Human | Polyclonal | Rabbit | Aminoadipate Aminotransferase (AADAT) | FITC | 162.5 | 20 µg | Q8N5Z0 | RUO | ||
Abbexa | AADAT | abx301574 | Aminoadipate Aminotransferase (AADAT) Antibody | Human | Polyclonal | Rabbit | Aminoadipate Aminotransferase (AADAT) | Unconjugated | ELISA, IHC | 162.5 | 20 µg | Q8N5Z0 | RUO | |
Abbexa | AADAT | abx110948 | Aminoadipate Aminotransferase (AADAT) Antibody | Human | Polyclonal | Rabbit | Aminoadipate Aminotransferase (AADAT) | Unconjugated | ELISA, IHC | 612.5 | 100 µl | Q8N5Z0 | RUO | |
Abbexa | AADAT | abx230018 | Aminoadipate Aminotransferase (AADAT) Antibody | Human | Polyclonal | Rabbit | Aminoadipate Aminotransferase (AADAT) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | Q8N5Z0 | RUO | |
Abbexa | AADAT | abx131228 | Aminoadipate Aminotransferase (AADAT) Antibody | Mouse | Polyclonal | Rabbit | Aminoadipate Aminotransferase (AADAT) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | AADAT | abx650511 | Human Aminoadipate Aminotransferase (AADAT) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 200 | 10 µg | Q8N5Z0 | RUO |
Abbexa | AADAT | abx650512 | Mouse Aminoadipate Aminotransferase (AADAT) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | Q9WVM8 | RUO |
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