Mouse Aminoadipate Aminotransferase (AADAT) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for AADAT
proveedor
Abbexareference
abx516042Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Aminoadipate Aminotransferase (AADAT) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Aminoadipate Aminotransferase (AADAT) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Aminoadipate aminotransferase (AADAT), also known as kynurenine aminotransferase II (KAT II), is a mitochondrial enzyme that catalyzes the transamination of kynurenine to kynurenic acid (KYNA), a neuroactive metabolite in the kynurenine pathway of tryptophan metabolism. KYNA acts as an antagonist of NMDA and alpha-7 nicotinic acetylcholine receptors, regulating excitotoxicity and neuroinflammation in the brain. AADAT is expressed in various tissues, with high activity in the brain, where it influences neurotransmission and neuroprotection. Dysregulation of AADAT or kynurenine pathway metabolites has been linked to neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and schizophrenia, as well as cancer and immune-related disorders.
Características del producto
category
ELISA Kits
immunogen target
Aminoadipate Aminotransferase (AADAT)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.079 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
KAT2,KATII,KYAT2,Kynurenine Aminotransferase II
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
AADAT
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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polyclonalTransaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine an...
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