Human Aminoadipate Aminotransferase (AADAT) ELISA Kit

Este producto es parte de AADAT - Aminoadipate Aminotransferase
Product Graph
643.5€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human Aminoadipate Aminotransferase (AADAT) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx150492
tested applications
ELISA

Description

Human Aminoadipate Aminotransferase (AADAT) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Aminoadipate Aminotransferase (AADAT) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Aminoadipate Aminotransferase (AADAT)

Documents del producto

Instrucciones
Descargar
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Aminoadipate Aminotransferase (AADAT)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.06 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
KAT2,KATII,KYAT2,Kynurenine Aminotransferase II
Background
Elisa kits for AADAT
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Aminoadipate aminotransferase (AADAT), also known as kynurenine aminotransferase II (KAT II), is a mitochondrial enzyme that catalyzes the transamination of kynurenine to kynurenic acid (KYNA), a neuroactive metabolite in the kynurenine pathway of tryptophan metabolism. KYNA acts as an antagonist of NMDA and alpha-7 nicotinic acetylcholine receptors, regulating excitotoxicity and neuroinflammation in the brain. AADAT is expressed in various tissues, with high activity in the brain, where it influences neurotransmission and neuroprotection. Dysregulation of AADAT or kynurenine pathway metabolites has been linked to neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and schizophrenia, as well as cancer and immune-related disorders.

Related Products

EH1430

Human AADAT (Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial) ELISA Kit

Ver Producto
FNab00018

AADAT antibody

Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor(in vitro).

Ver Producto
abx110948

Aminoadipate Aminotransferase (AADAT) Antibody

Aminoadipate Aminotransferase Antibody is a Rabbit Polyclonal antibody against Aminoadipate Aminotransferase.

Ver Producto