Human AADAT (Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial) ELISA Kit
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human AADAT (Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH1430
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.313-20ng/ml |
| Sensitivity | 0.188ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q8N5Z0 |
| Alias | KAT2,KATII,KYAT2,Kynurenine Aminotransferase II |
| Background | Elisa kits for AADAT |
| Status | RUO |
Background
Aminoadipate aminotransferase (AADAT), also known as kynurenine aminotransferase II (KAT II), is a mitochondrial enzyme that catalyzes the transamination of kynurenine to kynurenic acid (KYNA), a neuroactive metabolite in the kynurenine pathway of tryptophan metabolism. KYNA acts as an antagonist of NMDA and alpha-7 nicotinic acetylcholine receptors, regulating excitotoxicity and neuroinflammation in the brain. AADAT is expressed in various tissues, with high activity in the brain, where it influences neurotransmission and neuroprotection. Dysregulation of AADAT or kynurenine pathway metabolites has been linked to neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and schizophrenia, as well as cancer and immune-related disorders.
Productos relacionados
Aminoadipate Aminotransferase (AADAT) Antibody
Aminoadipate Aminotransferase Antibody is a Rabbit Polyclonal antibody against Aminoadipate Aminotransferase.…
Ver producto Aminoadipate Aminotransferase (AADAT) Antibody
Rabbit Polyclonal against the AADAT protein.…
Ver producto
Aminoadipate Aminotransferase (AADAT) Antibody
Aminoadipate Aminotransferase Antibody is a Rabbit Polyclonal against Aminoadipate Aminotransferase.…
Ver producto