Family main features
Acyl-CoA Synthetase Medium-Chain (ACSM) family members are enzymes involved in the metabolism of medium-chain fatty acids (MCFAs), typically ranging from 4 to 12 carbon atoms in length. These enzymes catalyze the activation of MCFAs by converting them into acyl-CoA derivatives. This activation step is crucial for the subsequent utilization of fatty acids in various metabolic pathways, including beta-oxidation for energy production or incorporation into cellular membranes for lipid synthesis. They also participate in the glycine conjugation pathway in the detoxification of ibuprofen (ACSM2A)
The structure of ACSM enzymes includes several key domains and motifs:
The ACSM family is classified based on substrate specificity and tissue distribution. Key members include:
ACSM enzymes serve essential functions in various metabolic processes:
ACSM enzymes interact with various molecules and metabolic pathways:
Alterations or deficiencies in ACSM enzymes can lead to several metabolic disorders:
The Acyl-CoA Synthetase Medium-Chain (ACSM) family includes enzymes essential for the activation of medium-chain fatty acids by converting them into acyl-CoA derivatives. This activation is crucial for fatty acid metabolism, including degradation, lipid biosynthesis, and energy production. Key members such as ACSM1, ACSM2A, ACSM2B, ACSM3, ACSM4, and ACSM5 each have specific roles and tissue distributions. Dysfunctions or mutations in these enzymes can lead to various metabolic disorders, emphasizing their importance in maintaining lipid homeostasis and energy balance. Understanding the structure, function, interactions, and clinical implications of ACSM enzymes provides valuable insights into their roles in metabolic processes and potential therapeutic applications.
Acyl-CoA synthetase medium chain family member 1(ACSM1)
BUCS1,MACS1
Acyl-CoA synthetase medium chain family member 2(ACSM2)
ACSM2,HXMA,HYST1046,A-923A4.1
Acyl-CoA synthetase medium chain family member 2A(ACSM2A)
ACSM2,HXMA,HYST1046,A-923A4.1
Acyl-CoA synthetase medium chain family member 2B(ACSM2B)
ACSM2,HXMA,HYST1046,A-923A4.1
Acyl-CoA synthetase medium chain family member 3(ACSM3)
SA,SAH,Butyrate CoA ligase 3
Acyl-CoA synthetase medium chain family member 4(ACSM4)
ACSM4
Acyl-CoA synthetase medium chain family member5(ACSM5)
ACSM5
Acyl-CoA synthetase medium chain family member 6(ACSM6)
C10orf129
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, ELISA Kits, Primary Antibodies) relacionados con ACSM - Acyl-CoA synthetase medium chain family member
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 38 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ACSM1 | abx500891 | Human Acyl-coenzyme A synthetase ACSM1, mitochondrial (ACSM1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q08AH1 | RUO | ||
Abbexa | ACSM2A | abx385597 | Human Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q08AH3 | RUO |
Abbexa | ACSM2B | abx500863 | Human Acyl-coenzyme A synthetase ACSM2B, mitochondrial (ACSM2B) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q68CK6 | RUO | ||
Abbexa | ACSM3 | abx385598 | Human Acyl-CoA Synthetase Medium-Chain Family Member 3 (ACSM3) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.313 ng/ml - 20 ng/ml | < 0.188 ng/ml | 687.5 | 96 tests | Q53FZ2 | RUO |
Abbexa | ACSM4 | abx500898 | Human Acyl-coenzyme A synthetase ACSM4, mitochondrial (ACSM4) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P0C7M7 | RUO | ||
Abbexa | ACSM5 | abx385599 | Human Acyl-CoA Synthetase Medium-Chain Family Member 5 (ACSM5) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q6NUN0 | RUO |
Abbexa | ACSM6 | abx500904 | Human Acyl-coenzyme A synthetase ACSM6, mitochondrial (ACSM6) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q6P461 | RUO | ||
Abbexa | ACSM1 | abx500892 | Mouse Acyl-coenzyme A synthetase ACSM1, mitochondrial (ACSM1) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q91VA0 | RUO | ||
Abbexa | ACSM2 | abx500893 | Mouse Acyl-coenzyme A synthetase ACSM2, mitochondrial (ACSM2) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8K0L3 | RUO | ||
Abbexa | ACSM3 | abx500896 | Mouse Acyl-coenzyme A synthetase ACSM3, mitochondrial (ACSM3) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q3UNX5 | RUO | ||
Abbexa | ACSM4 | abx500899 | Mouse Acyl-coenzyme A synthetase ACSM4, mitochondrial (ACSM4) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q80W40 | RUO | ||
Abbexa | ACSM5 | abx500902 | Mouse Acyl-coenzyme A synthetase ACSM5, mitochondrial (ACSM5) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8BGA8 | RUO | ||
Abbexa | ACSM2 | abx500894 | Rat Acyl-coenzyme A synthetase ACSM2, mitochondrial (ACSM2) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | O70490 | RUO | ||
Abbexa | ACSM3 | abx500897 | Rat Acyl-CoA Synthetase Medium-Chain Family Member 3 (ACSM3) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q6SKG1 | RUO | ||
Abbexa | ACSM4 | abx500900 | Rat Acyl-Coenzyme A Synthetase ACSM4, Mitochondrial (ACSM4) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q7TN78 | RUO | ||
Abbexa | ACSM5 | abx500903 | Rat Acyl-CoA Synthetase Medium-Chain Family Member 5 (ACSM5) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q6AYT9 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | ACSM2A | FNab00110 | anti- ACSM2A antibody | human | polyclonal | Rabbit | acyl-CoA synthetase medium-chain family member 2A | IgG | Unconjugated | ELISA, WB | 100µg | Q08AH3 | RUO | |
FineTest | ACSM3 | FNab00111 | anti- ACSM3 antibody | human | polyclonal | Rabbit | acyl-CoA synthetase medium-chain family member 3 | IgG | Unconjugated | ELISA, WB, IF, IHC, FC | 100µg | Q53FZ2 | RUO | |
FineTest | ACSM5 | FNab00112 | anti- ACSM5 antibody | human | polyclonal | Rabbit | acyl-CoA synthetase medium-chain family member 5 | IgG | Unconjugated | ELISA, WB, IHC | 100µg | Q6NUN0 | RUO | |
Abbexa | ACSM1 | abx175242 | Acyl Coenzyme A Synthetase Medium Chain Family, Member 1 (ACSM1) Antibody | Human | Polyclonal | Rabbit | Acyl Coenzyme A Synthetase Medium Chain Family, Member 1 (ACSM1) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | RUO | ||
Abbexa | ACSM1 | abx034308 | Acyl Coenzyme A Synthetase Medium Chain Family, Member 1 (ACSM1) Antibody | Human | Polyclonal | Rabbit | Acyl Coenzyme A Synthetase Medium Chain Family, Member 1 (ACSM1) | Unconjugated | ELISA, WB, FCM | 250 | 80 µl | Q08AH1 | RUO | |
Abbexa | ACSM2A | abx038123 | Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | ACSM2A | abx030539 | Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A) | Unconjugated | ELISA, WB | 250 | 80 µl | Q08AH3 | RUO | |
Abbexa | ACSM2A | abx230110 | Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A) | Unconjugated | ELISA, WB | 350 | 100 µg | Q08AH3 | RUO | |
Abbexa | ACSM3 | abx320494 | Acyl-CoA Synthetase Medium-Chain Family Member 3 (ACSM3) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Medium-Chain Family Member 3 (ACSM3) | Unconjugated | ELISA, IHC | 237.5 | 50 µl | Q53FZ2 | RUO | |
Abbexa | ACSM3 | abx037965 | Acyl-CoA Synthetase Medium-Chain Family Member 3 (ACSM3) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Medium-Chain Family Member 3 (ACSM3) | Unconjugated | ELISA, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | ACSM3 | abx322288 | Acyl-CoA Synthetase Medium-Chain Family Member 3 (ACSM3) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Medium-Chain Family Member 3 (ACSM3) | Unconjugated | ELISA, WB, IHC | 237.5 | 50 µl | Q53FZ2 | RUO | |
Abbexa | ACSM3 | abx230111 | Acyl-CoA Synthetase Medium-Chain Family Member 3 (ACSM3) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Medium-Chain Family Member 3 (ACSM3) | Unconjugated | ELISA, WB, IHC, IF/ICC, FCM | 350 | 100 µg | Q53FZ2 | RUO | |
Abbexa | ACSM3 | abx110797 | Acyl-CoA Synthetase Medium-Chain Family Member 3 (ACSM3) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Medium-Chain Family Member 3 (ACSM3) | Unconjugated | ELISA, WB | 612.5 | 100 µl | Q53FZ2 | RUO | |
Abbexa | ACSM4 | abx037395 | Acyl-Coenzyme A Synthetase ACSM4, Mitochondrial (ACSM4) Antibody | Human | Polyclonal | Rabbit | Acyl-Coenzyme A Synthetase ACSM4, Mitochondrial (ACSM4) | Unconjugated | ELISA, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | ACSM5 | abx038100 | Acyl-CoA Synthetase Medium-Chain Family Member 5 (ACSM5) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Medium-Chain Family Member 5 (ACSM5) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | ACSM5 | abx211734 | Acyl-CoA Synthetase Medium-Chain Family Member 5 (ACSM5) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Medium-Chain Family Member 5 (ACSM5) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | Q6NUN0 | RUO | |
Abbexa | ACSM5 | abx211733 | Acyl-CoA Synthetase Medium-Chain Family Member 5 (ACSM5) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Medium-Chain Family Member 5 (ACSM5) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | Q6NUN0 | RUO | |
Abbexa | ACSM5 | abx230112 | Acyl-CoA Synthetase Medium-Chain Family Member 5 (ACSM5) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Medium-Chain Family Member 5 (ACSM5) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | Q6NUN0 | RUO | |
Abbexa | ACSM4 | abx031248 | Acyl-Coenzyme A Synthetase ACSM4, Mitochondrial (ACSM4) Antibody | Mouse | Polyclonal | Rabbit | Acyl-Coenzyme A Synthetase ACSM4, Mitochondrial (ACSM4) | Unconjugated | ELISA, WB | 250 | 80 µl | P0C7M7 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ACSM1 | abx650424 | Human Acyl Coenzyme A Synthetase Medium Chain Family, Member 1 (ACSM1) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 200 | 10 µg | Q08AH1 | RUO |
FineTest | ACSM3 | P5936 | Recombinant Human ACSM3 | Human | Recombinant | E.Coli | Western Blot,ELISA | 50μg | Q53FZ2 | RUO | ||
FineTest | ACSM5 | P6034 | Recombinant Human ACSM5 | Human | Recombinant | E.Coli | Western Blot,ELISA | 50μg | Q6NUN0 | RUO |
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