Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A) Antibody
357.5€ (100 µg)
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Name
Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx038123
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the ACSM2A protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A) Immunogen: Recombinant fragment corresponding to 195-434 AA of human ACSM2A. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 64 kDa |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ACSM2,HXMA,HYST1046,A-923A4.1 |
| Background | Antibody anti-ACSM2A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACSM2A is a medium-chain acyl-CoA synthetase that activates fatty acids, particularly those with 4 to 12 carbon chain lengths, enabling their use in β-oxidation and lipid biosynthesis. Expressed predominantly in the liver and kidneys, ACSM2A is involved in metabolizing medium-chain fatty acids derived from dietary intake or endogenous lipid breakdown. It plays a critical role in energy production, particularly during metabolic states requiring rapid mobilization of energy sources, such as fasting or physical exertion. ACSM2A also participates in the detoxification of fatty acid derivatives and xenobiotics, contributing to overall metabolic homeostasis. Dysregulation of ACSM2A has been implicated in metabolic disorders and kidney function abnormalities, where impaired medium-chain fatty acid metabolism affects energy balance and organ function. Its enzymatic role emphasizes its importance in metabolic adaptability and lipid utilization.
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