Acyl Coenzyme A Synthetase Medium Chain Family, Member 1 (ACSM1) Antibody
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Description
Acyl Coenzyme A Synthetase Medium Chain Family, Member 1 (ACSM1) Antibody is a Rabbit Polyclonal antibody against Acyl Coenzyme A Synthetase Medium Chain Family, Member 1 (ACSM1).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Acyl Coenzyme A Synthetase Medium Chain Family, Member 1 (ACSM1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | BUCS1,MACS1 |
| Background | Antibody anti-ACSM1 |
| Status | RUO |
Descripción
ACSM1 is an enzyme that activates medium-chain fatty acids by converting them into acyl-CoA esters, a key step in their metabolism for β-oxidation and lipid biosynthesis. It is primarily expressed in the liver and kidneys, where it contributes to the catabolism of dietary medium-chain fatty acids and their incorporation into energy production pathways. ACSM1 supports metabolic flexibility by facilitating the rapid oxidation of medium-chain fatty acids during fasting or high-fat dietary conditions. It also plays a role in detoxification pathways by processing fatty acid derivatives and xenobiotics. Dysregulation of ACSM1 activity has been associated with metabolic imbalances, particularly in conditions where medium-chain fatty acid metabolism is impaired, such as certain forms of fatty acid oxidation disorders. Its specificity for medium-chain substrates highlights its role in maintaining energy homeostasis and lipid processing.
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