Human Acyl Coenzyme A Synthetase Medium Chain Family, Member 1 (ACSM1) Protein
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Description
Human ACSM1 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Acyl Coenzyme A Synthetase Medium Chain Family, Member 1 (ACSM1) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 24.4 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser370-Pro557 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q08AH1 |
| Alias | BUCS1,MACS1 |
| Background | Protein ACSM1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ACSM1 is an enzyme that activates medium-chain fatty acids by converting them into acyl-CoA esters, a key step in their metabolism for β-oxidation and lipid biosynthesis. It is primarily expressed in the liver and kidneys, where it contributes to the catabolism of dietary medium-chain fatty acids and their incorporation into energy production pathways. ACSM1 supports metabolic flexibility by facilitating the rapid oxidation of medium-chain fatty acids during fasting or high-fat dietary conditions. It also plays a role in detoxification pathways by processing fatty acid derivatives and xenobiotics. Dysregulation of ACSM1 activity has been associated with metabolic imbalances, particularly in conditions where medium-chain fatty acid metabolism is impaired, such as certain forms of fatty acid oxidation disorders. Its specificity for medium-chain substrates highlights its role in maintaining energy homeostasis and lipid processing.
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