Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A) Antibody
292.5€ (80 µl)
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Name
Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx030539
Tested Applications
ELISA, WB
Description
ACSM2A has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C (4) to C (11) and on the corresponding 3-hydroxy-and 2, 3-or 3, 4-unsaturated acids (in vitro) (By similarity).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A) Immunogen: KLH-conjugated synthetic peptide between 41-67 amino acids from the N-terminal region of human ACSM2A. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 64.2 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q08AH3 |
| Alias | ACSM2,HXMA,HYST1046,A-923A4.1 |
| Background | Antibody anti-ACSM2A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACSM2A is a medium-chain acyl-CoA synthetase that activates fatty acids, particularly those with 4 to 12 carbon chain lengths, enabling their use in β-oxidation and lipid biosynthesis. Expressed predominantly in the liver and kidneys, ACSM2A is involved in metabolizing medium-chain fatty acids derived from dietary intake or endogenous lipid breakdown. It plays a critical role in energy production, particularly during metabolic states requiring rapid mobilization of energy sources, such as fasting or physical exertion. ACSM2A also participates in the detoxification of fatty acid derivatives and xenobiotics, contributing to overall metabolic homeostasis. Dysregulation of ACSM2A has been implicated in metabolic disorders and kidney function abnormalities, where impaired medium-chain fatty acid metabolism affects energy balance and organ function. Its enzymatic role emphasizes its importance in metabolic adaptability and lipid utilization.
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