Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A) Antibody

Este producto es parte de ACSM - Acyl-CoA synthetase medium chain family member
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292.5€ (80 µl)

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935106861
info@markelab.com
name
Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx030539
tested applications
ELISA, WB

Description

ACSM2A has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C (4) to C (11) and on the corresponding 3-hydroxy-and 2, 3-or 3, 4-unsaturated acids (in vitro) (By similarity).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Acyl-CoA Synthetase Medium-Chain Family Member 2A (ACSM2A)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified through a protein A column, followed by peptide affinity purification.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q08AH3
Alias
ACSM2,HXMA,HYST1046,A-923A4.1
Background
Antibody anti-ACSM2A
Status
RUO

Descripción

ACSM2A is a medium-chain acyl-CoA synthetase that activates fatty acids, particularly those with 4 to 12 carbon chain lengths, enabling their use in β-oxidation and lipid biosynthesis. Expressed predominantly in the liver and kidneys, ACSM2A is involved in metabolizing medium-chain fatty acids derived from dietary intake or endogenous lipid breakdown. It plays a critical role in energy production, particularly during metabolic states requiring rapid mobilization of energy sources, such as fasting or physical exertion. ACSM2A also participates in the detoxification of fatty acid derivatives and xenobiotics, contributing to overall metabolic homeostasis. Dysregulation of ACSM2A has been implicated in metabolic disorders and kidney function abnormalities, where impaired medium-chain fatty acid metabolism affects energy balance and organ function. Its enzymatic role emphasizes its importance in metabolic adaptability and lipid utilization.

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