Human Acyl-coenzyme A synthetase ACSM1, mitochondrial (ACSM1) ELISA Kit
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Description
Human Acyl-coenzyme A synthetase ACSM1, mitochondrial (ACSM1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acyl-coenzyme A synthetase ACSM1, mitochondrial (ACSM1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Acyl-coenzyme A synthetase ACSM1, mitochondrial (ACSM1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q08AH1 |
| Gene ID | 116285 |
| OMIM | 614357 |
| Alias | BUCS1,MACS1 |
| Background | Elisa kits for ACSM1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACSM1 is an enzyme that activates medium-chain fatty acids by converting them into acyl-CoA esters, a key step in their metabolism for β-oxidation and lipid biosynthesis. It is primarily expressed in the liver and kidneys, where it contributes to the catabolism of dietary medium-chain fatty acids and their incorporation into energy production pathways. ACSM1 supports metabolic flexibility by facilitating the rapid oxidation of medium-chain fatty acids during fasting or high-fat dietary conditions. It also plays a role in detoxification pathways by processing fatty acid derivatives and xenobiotics. Dysregulation of ACSM1 activity has been associated with metabolic imbalances, particularly in conditions where medium-chain fatty acid metabolism is impaired, such as certain forms of fatty acid oxidation disorders. Its specificity for medium-chain substrates highlights its role in maintaining energy homeostasis and lipid processing.
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