Family main features
Members of this family exhibit elongated N-termini and harbor multiple functional domains. They are implicated in immune system functions and central nervous system activities. Through alternative splicing, numerous transcript variants are generated, encoding diverse isoforms.ADGRG1 is a member of the G protein-coupled receptor family and regulates brain cortical patterning. Binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. is linked to diseases such as Cortical Dysplasia, Complex, With Other Brain Malformations .ADGRG2 is a G protein-coupled receptor family member recognized as an epididymis-specific transmembrane protein. It may undergo proteolytic processing, as indicated by the presence of a motif known to facilitate protein scission in certain family members
ADGRG receptors share common structural features typical of adhesion GPCRs:
The ADGRG subfamily includes several members:
These receptors are classified based on their specific extracellular adhesion domains and their tissue-specific expression patterns.
ADGRG receptors have diverse and significant roles:
ADGRG receptors interact with a variety of molecules to perform their functions:
Alterations in ADGRG receptor function or expression are linked to various diseases:
ADGRG receptors, part of the adhesion GPCR family, are essential for mediating cell adhesion, signaling, and various physiological processes. They are characterized by extended extracellular domains with adhesion motifs, a 7-transmembrane domain, and intracellular regions for signaling. ADGRG receptors play crucial roles in cell adhesion, signal transduction, development, immune regulation, and nervous system function. Dysregulation of these receptors is associated with cancer, neurological disorders, cardiovascular diseases, immune disorders, and musculoskeletal disorders. Understanding the structure, function, and interactions of ADGRG receptors provides insights into their roles in health and disease.
Adhesion G-protein coupled receptor G1(ADGRG1)
ADGRG1,BFPP,Cyt28,GPR56,TM7LN4,TM7XN1,BPPR,CDCBM14B,CDCBM15A
Adhesion G-protein coupled receptor G2(ADGRG2)
ADGRG2,GPR64,HE6,TM7LN2,CBAVDX, EDDM6
Adhesion G-protein coupled receptor G3(ADGRG3)
ADGRG3,PB99,GPR97,PGR26
Adhesion G-protein coupled receptor G4(ADGRG4)
ADGRG4,GPR112
Adhesion G-protein coupled receptor G5(ADGRG5)
ADGRG5,PGR27,GPR114,Gm1109,UNQ2524/PRO6017
Adhesion G-protein coupled receptor G6(ADGRG6)
ADGRG6,developmentally regulated GPCR,DREG,GPR126 ,vascular inducible GPCR,VIGR, APG1,PS1TP2
Adhesion G-protein coupled receptor G7(ADGRG7)
ADGRG7,GPR128
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits) relacionados con ADGRG - Adhesion G-protein coupled receptor G
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 37 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ADGRG1 | abx526041 | Human G-protein coupled receptor 56 (ADGRG1) ELISA Kit | Human | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q9Y653 | RUO | ||
Abbexa | ADGRG2 | abx526053 | Human Adhesion G Protein-Coupled Receptor G2 (ADGRG2) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.09 ng/ml | 687.5 | 96 tests | Q8IZP9 | RUO |
Abbexa | ADGRG3 | abx526075 | Human Adhesion G Protein-Coupled Receptor G3 (ADGRG3) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.78 ng/ml - 50 ng/ml | < 0.35 ng/ml | 687.5 | 96 tests | Q86Y34 | RUO |
Abbexa | ADGRG4 | abx525782 | Human Probable G-protein coupled receptor 112 (ADGRG4) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8IZF6 | RUO | ||
Abbexa | ADGRG5 | abx525786 | Human Probable G-protein coupled receptor 114 (ADGRG5) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8IZF4 | RUO | ||
Abbexa | ADGRG6 | abx525800 | Human Adhesion G Protein-Coupled Receptor G6 (ADGRG6) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q86SQ4 | RUO | ||
Abbexa | ADGRG7 | abx525802 | Human Probable G-protein coupled receptor 128 (ADGRG7) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q96K78 | RUO | ||
Abbexa | ADGRG1 | abx526042 | Mouse G-protein coupled receptor 56 (ADGRG1) ELISA Kit | Mouse | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8K209 | RUO | ||
Abbexa | ADGRG2 | abx526054 | Mouse G-protein coupled receptor 64 (ADGRG2) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8CJ12 | RUO | |
Abbexa | ADGRG3 | abx526076 | Mouse Adhesion G Protein-Coupled Receptor G3 (ADGRG3) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.07 ng/ml | 687.5 | 96 tests | Q8R0T6 | RUO |
Abbexa | ADGRG4 | abx525783 | Mouse Probable G-protein coupled receptor 112 (ADGRG4) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | B7ZCC9 | RUO | ||
Abbexa | ADGRG5 | abx525787 | Mouse Probable G-protein coupled receptor 114 (ADGRG5) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q3V3Z3 | RUO | ||
Abbexa | ADGRG6 | abx525801 | Mouse Adhesion G Protein-Coupled Receptor G6 (ADGRG6) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q6F3F9 | RUO | ||
Abbexa | ADGRG7 | abx525803 | Mouse Probable G-protein coupled receptor 128 (ADGRG7) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8BM96 | RUO | ||
Abbexa | ADGRG1 | abx526043 | Rat Adhesion G Protein-Coupled Receptor G1 (ADGRG1) ELISA Kit | Rat | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8K3V3 | RUO | ||
Abbexa | ADGRG2 | abx526055 | Rat Adhesion G Protein-Coupled Receptor G2 (ADGRG2) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q8CJ11 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ADGRG1 | abx340771 | Adhesion G-protein coupled receptor G1 (ADGRG1) Antibody | Human | Polyclonal | Rabbit | Adhesion G-protein coupled receptor G1 (ADGRG1) | Unconjugated | ELISA, IHC, IF/ICC | 162.5 | 20 µg | Q9Y653 | RUO | |
Abbexa | ADGRG1 | abx340773 | Adhesion G-protein coupled receptor G1 (ADGRG1) Antibody (FITC) | Human | Polyclonal | Rabbit | Adhesion G-protein coupled receptor G1 (ADGRG1) | FITC | 162.5 | 20 µg | Q9Y653 | RUO | ||
Abbexa | ADGRG1 | abx324243 | Adhesion G Protein-Coupled Receptor G1 (ADGRG1) Antibody | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor G1 (ADGRG1) | Unconjugated | ELISA, WB, IF/ICC | 187.5 | 50 µg | Q9Y653 | RUO | |
Abbexa | ADGRG1 | abx340774 | Adhesion G-protein coupled receptor G1 (ADGRG1) Antibody (Biotin) | Human | Polyclonal | Rabbit | Adhesion G-protein coupled receptor G1 (ADGRG1) | Biotin | ELISA | 162.5 | 20 µg | Q9Y653 | RUO | |
Abbexa | ADGRG1 | abx340772 | Adhesion G-protein coupled receptor G1 (ADGRG1) Antibody (HRP) | Human | Polyclonal | Rabbit | Adhesion G-protein coupled receptor G1 (ADGRG1) | HRP | ELISA | 162.5 | 20 µg | Q9Y653 | RUO | |
Abbexa | ADGRG2 | abx210326 | Adhesion G Protein-Coupled Receptor G2 (ADGRG2) Antibody | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor G2 (ADGRG2) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q8IZP9 | RUO | |
Abbexa | ADGRG3 | abx029301 | G-Protein Coupled Receptor 97 (GPR97) Antibody | Human | Polyclonal | Rabbit | G-Protein Coupled Receptor 97 (GPR97) | Unconjugated | ELISA, WB | 281.25 | 80 µl | Q86Y34 | RUO | |
Abbexa | ADGRG3 | abx346886 | Adhesion G protein-coupled receptor G3 (ADGRG3) Antibody | Human | Polyclonal | Rabbit | Adhesion G protein-coupled receptor G3 (ADGRG3) | Unconjugated | ELISA | 162.5 | 20 µg | Q86Y34 | RUO | |
Abbexa | ADGRG3 | abx346887 | Adhesion G protein-coupled receptor G3 (ADGRG3) Antibody (HRP) | Human | Polyclonal | Rabbit | Adhesion G protein-coupled receptor G3 (ADGRG3) | HRP | ELISA | 162.5 | 20 µg | Q86Y34 | RUO | |
Abbexa | ADGRG3 | abx346889 | Adhesion G protein-coupled receptor G3 (ADGRG3) Antibody (Biotin) | Human | Polyclonal | Rabbit | Adhesion G protein-coupled receptor G3 (ADGRG3) | Biotin | ELISA | 162.5 | 20 µg | Q86Y34 | RUO | |
Abbexa | ADGRG3 | abx346888 | Adhesion G protein-coupled receptor G3 (ADGRG3) Antibody (FITC) | Human | Polyclonal | Rabbit | Adhesion G protein-coupled receptor G3 (ADGRG3) | FITC | 162.5 | 20 µg | Q86Y34 | RUO | ||
Abbexa | ADGRG5 | abx324351 | Adhesion G Protein-Coupled Receptor G5 (ADGRG5) Antibody | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor G5 (ADGRG5) | Unconjugated | ELISA, WB, IF/ICC | 187.5 | 50 µg | Q8IZF4 | RUO | |
Abbexa | ADGRG6 | abx324946 | Adhesion G Protein-Coupled Receptor G6 (ADGRG6) Antibody | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor G6 (ADGRG6) | Unconjugated | ELISA, WB, IHC, IF/ICC | 187.5 | 50 µg | Q86SQ4 | RUO | |
Abbexa | ADGRG6 | abx015298 | Adhesion G Protein-Coupled Receptor G6 (ADGRG6) Antibody | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor G6 (ADGRG6) | Unconjugated | ELISA, WB | 43.75 | 10 µg | Q86SQ4 | RUO | |
Abbexa | ADGRG6 | abx321238 | Adhesion G Protein-Coupled Receptor G6 (ADGRG6) Antibody | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor G6 (ADGRG6) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q86SQ4 | RUO | |
Abbexa | ADGRG6 | abx322643 | Adhesion G Protein-Coupled Receptor G6 (ADGRG6) Antibody | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor G6 (ADGRG6) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | Q86SQ4 | RUO | |
Abbexa | ADGRG6 | abx325690 | Adhesion G Protein-Coupled Receptor G6 (ADGRG6) Antibody | Human | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor G6 (ADGRG6) | Unconjugated | ELISA, WB, IF/ICC | 187.5 | 50 µg | Q86SQ4 | RUO | |
Abbexa | ADGRG6 | abx125899 | Adhesion G Protein-Coupled Receptor G6 (ADGRG6) Antibody | Mouse | Polyclonal | Rabbit | Adhesion G Protein-Coupled Receptor G6 (ADGRG6) | Unconjugated | WB | 175 | 20 µl | Q86SQ4 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ADGRG1 | abx692183 | Human G-Protein Coupled Receptor 56 (GPR56) Protein | Human | Recombinant | HEK293 cells | SDS-PAGE | 837.5 | 100 µg | RUO | ||
FineTest | ADGRG5 | P6162 | Recombinant Human GPR114 | Human | Recombinant | E.Coli | Western Blot,ELISA | 50μg | Q8IZF4 | RUO | ||
Abbexa | ADGRG5 | abx691261 | Human G-Protein Coupled Receptor 114 (GPR114) Protein | Human | Recombinant | HEK293 cells | SDS-PAGE | 837.5 | 100 µg | Q8IZF4 | RUO |
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