Adhesion G Protein-Coupled Receptor G1 (ADGRG1) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Adhesion G Protein-Coupled Receptor G1 (ADGRG1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx324243
tested applications
ELISA, WB, IF/ICC
Description
GPR56 Antibody is a Rabbit Polyclonal against GPR56.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adhesion G Protein-Coupled Receptor G1 (ADGRG1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y653 |
| Gene ID | 9289 |
| Alias | ADGRG1,BFPP,Cyt28,GPR56,TM7LN4,TM7XN1,BPPR,CDCBM14B,CDCBM15A |
| Background | Antibody anti-ADGRG1 |
| Status | RUO |
Descripción
Members of this family exhibit elongated N-termini and harbor multiple functional domains. They are implicated in immune system functions and central nervous system activities. Through alternative splicing, numerous transcript variants are generated, encoding diverse isoforms. ADGRG1, also known as GPR56, is a member of the adhesion GPCR family widely expressed in the central nervous system, immune cells, and various tissues. It plays crucial roles in brain development, particularly in cortical formation. ADGRG1 also regulates cell adhesion, migration, and tumor progression. Mutations in ADGRG1 are associated with bilateral frontoparietal polymicrogyria (BFPP), a neurological disorder. Beyond its developmental role, ADGRG1 has been implicated in cancer and immune modulation, making it a target of interest for therapeutic interventions.
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