Human G-Protein Coupled Receptor 56 (GPR56) Protein

Este producto es parte de ADGRG - Adhesion G-protein coupled receptor G
Product Graph
1079€ (100 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human G-Protein Coupled Receptor 56 (GPR56) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx692183
tested applications
SDS-PAGE

Description

Human GPR56 Protein is a recombinant protein from Human produced in HEK293 Cells. A DNA sequence encoding the human GPR56 isoform b (NP_958933.1) extracellular domain (Met 1-Val 342) was fused with a polyhistidine tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
GPR56
Host
HEK293 cells
Origin
Human
Observed MW
Molecular Weight: 37.4 kDa
Sequence Fragment: Met1-Val342
Tag: C-terminal His tag
Validity: The validity for this protein is 12 months.
Expression
Recombinant
Purity
> 80% (SDS-PAGE)
Size 1
100 µg
Form
Tested Applications
SDS-PAGE
Buffer
Lyophilized from sterile PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
NP_958933.1
Alias
ADGRG1,BFPP,Cyt28,GPR56,TM7LN4,TM7XN1,BPPR,CDCBM14B,CDCBM15A
Background
Protein ADGRG1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Members of this family exhibit elongated N-termini and harbor multiple functional domains. They are implicated in immune system functions and central nervous system activities. Through alternative splicing, numerous transcript variants are generated, encoding diverse isoforms. ADGRG1, also known as GPR56, is a member of the adhesion GPCR family widely expressed in the central nervous system, immune cells, and various tissues. It plays crucial roles in brain development, particularly in cortical formation. ADGRG1 also regulates cell adhesion, migration, and tumor progression. Mutations in ADGRG1 are associated with bilateral frontoparietal polymicrogyria (BFPP), a neurological disorder. Beyond its developmental role, ADGRG1 has been implicated in cancer and immune modulation, making it a target of interest for therapeutic interventions.
Related Products
abx324243
Adhesion G Protein-Coupled Receptor G1 (ADGRG1) Antibody
GPR56 Antibody is a Rabbit Polyclonal against GPR56.
Ver Producto
abx340771
Adhesion G-protein coupled receptor G1 (ADGRG1) Antibody
Adhesion G-protein coupled receptor G1 (ADGRG1) Antibody is a Rabbit Polyclonal antibody for the detection of Human ADGRG1.
Ver Producto
abx340772
Adhesion G-protein coupled receptor G1 (ADGRG1) Antibody (HRP)
Adhesion G-protein coupled receptor G1 (ADGRG1) Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP for the detection of Human ADGRG1.
Ver Producto