Adhesion G Protein-Coupled Receptor G6 (ADGRG6) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
Adhesion G Protein-Coupled Receptor G6 (ADGRG6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx015298
tested applications
ELISA, WB
Description
Rabbit polyclonal antibody against ADGRG6 protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adhesion G Protein-Coupled Receptor G6 (ADGRG6) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q86SQ4 |
| Gene ID | 57211 |
| OMIM | 606255 |
| Alias | ADGRG6,developmentally regulated GPCR,DREG,GPR126 ,vascular inducible GPCR,VIGR, APG1,PS1TP2 |
| Background | Antibody anti-ADGRG6 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Members of this family exhibit elongated N-termini and harbor multiple functional domains. They are implicated in immune system functions and central nervous system activities. Through alternative splicing, numerous transcript variants are generated, encoding diverse isoforms. ADGRG6, or GPR126, is a key player in Schwann cell development, peripheral nerve myelination, and vascular formation. It is widely expressed in endothelial cells and nervous tissues, where it regulates angiogenesis and nerve repair. Mutations in ADGRG6 are linked to conditions such as arthrogryposis multiplex congenita, a congenital joint contracture disorder. ADGRG6 also has implications in tumor angiogenesis, making it a target for cancer research and regenerative therapies.
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