Human G-Protein Coupled Receptor 114 (GPR114) Protein
1079€ (100 µg)
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935106861
info@markelab.com
name
Human G-Protein Coupled Receptor 114 (GPR114) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691261
tested applications
SDS-PAGE
Description
Human GPR114 Protein is a recombinant protein from Human produced in HEK293 Cells. A DNA sequence encoding the human GPR114 (Q8IZF4) (Met1-Gly184) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | GPR114 |
| Host | HEK293 cells |
| Origin | Human |
| Observed MW | Molecular Weight: 45.6 kDa Sequence Fragment: Met1-Gly184 Tag: C-terminal Fc tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 94% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8IZF4 |
| Alias | ADGRG5,PGR27,GPR114,Gm1109,UNQ2524/PRO6017 |
| Background | Protein ADGRG5 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Members of this family exhibit elongated N-termini and harbor multiple functional domains. They are implicated in immune system functions and central nervous system activities. Through alternative splicing, numerous transcript variants are generated, encoding diverse isoforms. ADGRG5, also known as GPR114, is expressed in immune cells such as eosinophils and has a role in modulating immune responses. It is particularly involved in allergic inflammation, contributing to immune cell adhesion and migration. ADGRG5 is under investigation for its potential role in asthma and other allergic disorders. Its specific signaling pathways are not fully elucidated, but its immune-related functions make it a promising target for therapies in allergic and inflammatory conditions.
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